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Main principles of Tropical Medicine and Parasitic Diseases Endemic in Sudan and how to control and manage clinical cases.
Sudan (MedSIN-Sudan ) - University of Gezira, Wad Medani, Gezira
Blue Nile National Institute for Communicable Diseases
Professor Bakri Yousif
Dr. Hassan Hamdi Suliman Dr. Hiba Bakri Professor Samira Hamid Abdelrahman Professor Bakri Yousif
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
Tropical medicine is an interdisciplinary branch of medicine that deals with health issues that occur uniquely, are more widespread, or are more difficult to control in tropical and subtropical regions. Physicians in this field diagnose and treat a variety of diseases and ailments. Most infections they deal with are endemic to the tropics. A few of the most well-known include malaria, HIV/AIDS, and tuberculosis. They must be knowledgeable in the 18 lesser-known neglected tropical diseases, which include Chagas disease, rabies, and dengue. Poor living conditions in underdeveloped tropical countries have led to a rising number of non-communicable diseases. These diseases include cancer and cardiovascular disease, which, in the past, have been more of a worry in developed countries. Physicians trained in tropical medicine must also be prepared to diagnose and treat these diseases. Malaria, leishmania and other parasitic diseases is an endemic disease in Sudan particularly in Gezira State so this research topic is very important based on a problem which all Sudanese citizens suffer from these diseases.
What is the aim of the project?
The project aims to study the parasitic diseases endemic in Sudan, to prevent and control parasitic diseases and to improve health in developing countries.
What techniques and methods are used?
A- The first step is to detect the parasites by lab techniques like: 1- Microscopy For many years, microscopy has been the only tool available for the detection of parasites through inspection of blood smears , tissue specimens , feces, lymph node aspirates , bone marrow , and even cerebrospinal fluid . 2-Serology-Based Assays In situations where biologic samples or tissue specimens are unavailable, serology alone is the gold standard for diagnosis. Serology-based diagnosis tools can be divided into two categories: antigen-detection assays and antibody-detection assays. These include the enzyme-linked immunosorbent assay (ELISA), also called enzyme immunoassay (EIA). 3-Falcon Assay Screening Test ELISA (FAST-ELISA) The Falcon assay screening test ELISA (FAST-ELISA) consists of using synthetic and recombinant peptides to evaluate antibody responses to an antigen . In the past, the method has been applied to the study of malaria , fasciolosis , schistosomiasis . B- The second step is to control the parasitic diseases: The principle of managemental control of parasites is to prevent pasture contamination, thereby preventing the parasite from completing its life-cycle in the host. The most effective was of reducing the spread of contamination is a combination of three factors: Use of anthelmintic (by administered about every 2 months during competitive season and one prophylactic treatment against small strongyles). To suppress faecal egg counts. Good pasture management (by training staff). Monitoring of parasite transmission.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- If the project includes “lab work”
- the student will take active part in the practical aspect of the project
- If the project is clinical
- the student will take active part in the clinical examination
- If the project is clinical
- the student will be allowed to work with patients
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Microscopic detection of parasites (by taking samples in the lab and doing microscopic examination under supervision of the tutor and the lab team), participating in the "Parasitic Control Program" (by taking physical visits to target areas with the student's team), working in small groups to review scientific research articles then implementing the outputs in the research project, active participation in Wad Medani teaching hospital to collect samples then work in the lab to detect the parasites, participating in the treatment protocol, studying and following the medical staff guidelines.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
60% Lab work (practical) 20% Clinical 10% Group Work 10% Interactive sessions (theoretical part will be presented by tutors twice a week).
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Medical student. Basic principles of lab work.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Students in biomedical fields
- Tropical Medicine and Parasitology. J R Soc Med. 2002.Aug; 95(8): 424. .PMCID: PMC1279976
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