Assessment of the effectiveness of chemical necrectomy using 40% benzoic acid in patients with burns
Czech Repiblic (IFMSA CZ) - Masaryk University, Brno
General Surgery
Department of Burns and Plastic Surgery, University Hospital Brno, Jihlavská 20, 625 00, Czech Republic
Doc. MUDr. Břetislav Lipový, Ph.D., MBA
Doc. MUDr. Břetislav Lipový, Ph.D., MBA
English, Czech, Slovak
4 weeks
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
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Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Burns are the most complex injury in human traumatology. For successful treatment of this trauma it is necessary to combine several points - system and local approach. The biggest challenge for all burn teams worldwide is the rapid and selective removal of necrotic tissue from the wound bed. The presence of necrotic tissue in the wound represents a high risk for the development of infectious complications because necrosis itself is an excellent growth medium for a variety of potentially pathogenic microorganisms. 40% benzoic acid is a very promising alternative to surgical necrectomy that meets all modern requirements for effective and selective necrectomy.
What is the aim of the project?
Learn how to handle 40% benzoic acid during application and subsequent chemical necrectomy. Evaluate the effectiveness of this methodology and determine advantages over conventional approaches to removing necrotic tissue.
What techniques and methods are used?
Application of 40% benzoic acid and subsequent manipulation within the chemical necrectomy during general anesthesia in the operating room and subsequent wound-management (split-thickness skin graft, supporting spontaneously healing process etc.)
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- If the project is clinical
- the student will be allowed to work with patients
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The student should become a regular member of a team in OR, previous experience in OR and operation technique is beneficial for a student. At the same time, the student will also participate in work around specific patients undergoing chemical necrectomy in the standard department and ICU including analgesic, fluid and antimicrobial management.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
There will be a required work with scientific literature during the stay.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic surgical skills, orientation in OR and knowledge about aseptic procedures, problem-solving abilities and work with literature
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
- Jelínková; Z.; et al. "OUR EXPERIENCE WITH THE USE OF 40% BENZOIC ACID FOR NECRECTOMY IN DEEP BURNS." Acta chirurgiae plasticae 59.1 (2017): 5-10.
- Dastych; Milan; et al. "Resorption and elimination kinetics of benzoic acid during chemical necrectomy in deep burns." Scandinavian journal of clinical and laboratory investigation 69.8 (2009): 827-830.