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Outcome Therapy Drug Resistant TB Patients to Shorten Therapy Regiment Compared to Individual
Indonesia (CIMSA-ISMKI) - Universitas Brawidjaya, Malang
Pulmonology and Respiratory Medicine, Faculty of Medicine, Brawijaya University, Malang, Indonesia. Address: Saiful Anwar General Hospital, IRNA 1 Education Building, 3rd Floor.
Yani Jane Sugiri, Ungky Agus Setyawan
Yani Jane Sugiri, Ungky Agus Setyawan
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
The incidence of drug resistant TB in Indonesia is getting higher. Data shows Indonesia ranks 5th in the world with the highest incidence of drug resistant TB. There are quite a lot of drug resistant TB patients at Saiful Anwar Hospital, this is because Saiful Anwar Hospital is one of the reference centers for drug resistant TB. Treatment of drug resistant TB patients is quite difficult, using 2nd line drugs. Side effects of 2nd line drugs are also quite a lot compared to 1st line drugs. Current treatment methods that are applied nationally in Indonesia use 2 kinds of regimens. Shorten therapy regiment (STR ) or individual therapy if the patient is unfit or fails to use STR.
What is the aim of the project?
The purpose of this research is to analyze the therapeutic outcomes in patients with drug resistant TB when using STR compared to individuals as well as looking at the factors that contribute to the success of therapy.
What techniques and methods are used?
This study retrospectively analyzed drug resistant TB patients in 2018-2019 by taking data on drug resistant TB medical records of patients at Saiful Anwar Hospital Malang. The sample of the study was patients with drug resistant TB who obtained the STR regimen and individually in 2018-2019. Record all patient demographic data and factors that influence the success of therapy. Analyzing the success of therapy by looking at clinical conditions based on clinical and bacteriological and the final results of treatment. All side effects that arise also in the data, so they can see the correlation of therapeutic success.
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Students can see directly the clinical condition of drug resistant TB patients who are undergoing chemotherapy (STR and Individual). Students can study the clinical condition of drug resistant TB patients in outline. Students can interact (HT & PE) with drug resistant TB patients in treatment settings at the hospital. Student can analyze the data obtained. Students will learn about controlling infection in TB, drug resistant TB therapy, community activists for drug resistant TB treatment and treatment of side effects of drugs in hospitals
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Before the activity takes place, students will be explained in detail the research protocol and the basics of the research. Students will also be taught theoretically about drug resistant TB and drug resistant TB in Indonesia. Students during the study take place and when data collection to patients is always under supervision and directed its tasks.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster - The student will prepare a presentation - The student will prepare a scientific report - The student will prepare an abstract
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Know the basic theory of research methodology and good clinical practice (GCP)
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system
- https://www.tbindonesia.or.id/page/view/22/tb-mdr https://www.who.int/tb/areas-of-work/drug-resistant-tb/en/
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