Projects
Name
Herbal plant for antioxidant and antibacterial disease
University
Indonesia (CIMSA-ISMKI) - Universitas Yarsi, Jakarta
Domain
Biochemistry
Departement
Herbal Research Centre of YARSI university, 11th Floor, Menara YARSI, Kav. 13, Jl. Let. Jend. Suprapto. Cempaka Putih, Jakarta Pusat, DKI Jakarta. Indonesia. 10510
Head
Dr. Juniarti, M.Si
Tutor
Dr. Juniarti, M.Si
Languages
Indonesian, English
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No No No No No No Yes Yes Yes Yes No
Type of Research Project
- Basic science
What is the background of the project?
The potential of bioactive compound and extract from teresterial plant has been extensively investigated in recent years. natural products have been used since ancient times and in folklore for the treatment of many diseases and illnesses. Classical natural product chemistry methodologies enabled a vast array of bioactive secondary metabolites from terrestrial and marine sources to be discovered. Many of these natural products have gone on to become current drug candidates. This brief review aims to highlight historically significant bioactive marine and terrestrial natural products, their use in folklore and dereplication techniques to rapidly facilitate their discovery. Furthermore a discussion of how natural product chemistry has resulted in the identification of many drug candidates; the application of advanced hyphenated spectroscopic techniques to aid in their discovery, the future of natural product chemistry and finally adopting metabolomic profiling and dereplication approaches for the comprehensive study of natural product extracts will be discussed.
What is the aim of the project?
The purpose of the project is to determine phytochemical content from medicinal plantpo and bioactivity for certain diseases.
What techniques and methods are used?
The common methods step in herbal studies 1. Extraction from plant to be crude extract 2. Phytochemical assay with specific reagen 3. Antioxidant assay with DPPH method 4. Determination of total phenolic 5. Separation bioactive compound from extract with Thin layer Chromatography (TLC) and Radial Chromatography .
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks of the student will be performed on his/her own
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The student are requires to reading journal or acticle review about bioactive phytochemical. In addition the student might be required to make a presentation under supervision of the tutor. Hnese must be completed before tne end of the excelent period, checked by the tutor and sent the taks to LORE. There are several steps that the student will do during the research 1. Informed consent to participants 2. Laboratory works (extraction, phytochemical test, antioxidant assay, antibacterial assay and separation of bioactive compound) 3. Reporting
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Yes, student will be attending our group meeting and supervisor wil explain about the project including the preliminary reading and basic information of the project
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster
- The student will prepare a scientific report
- The student’s name will be mentioned in a future publication
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Student with high curiosity, high motivated and good attitude can apply the program
Are there any legal limitations in the student’s involvement
No
Hours
6
Type of students accepted
This project accepts:
- Students in biomedical fields
- Dental medicine students (IADS members)
Articles
- Juniarti; Aryenti; Suryadi; Harijadi; and Yuhernita . 2012. PMN Leukocytes and Fibroblasts Numbers on Wound Burn Healing on the Skinof White Rat after Administration of Ambonese Plantain Banana; Jakarta : Makara Journal of Science Vol 16; no. 1.
- Juniarti; Aryenti; Yuhernita; Ernie Hernawati Poerwaningsih; Ahmad Aulia Jusuf; Hans-Joachim Freisleben; and Mohamad Sadikin . 2012. Effects of Methanolic Jatropha multifida L. Extract in Wound Healing Assessed by the Total Number of PMN Leukocytes and Fibroblasts. Jakarta : Makara Journal of Science Vol 16; no. 3