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Development of a New Scoring System to Predict the Severity of Coronary Artery Disease
Indonesia (CIMSA-ISMKI) - Universitas Airlangga, Surabaya
Department of Cardiology and Vascular Medicine, RSUD Dr. Soetomo – Faculty of Medicine Universitas Airlangga, Jawa Timur
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Coronary artery disease (CAD) remained the top cause of mortality and morbidity for a person aged 35 and over worldwide [1,2]. Failure to detect CAD and provide early treatment may cause CAD treatment to become more expensive and higher mortality rate . It is estimated that around one-third of middle ages population in the USA will suffer from CAD manifestation . In Indonesia, the Indonesian Ministry of Health also showed that CAD responsible for 12.9% of death . Determining the best risk factor assessment for CAD is extremely important for early prevention and treatment. The screening for the CAD using angiography is easily available in the developed countries with short waiting lists. However, in the developing countries, the awareness and accessibility of the cardiovascular disease screening is still low . To obtain cost-effective prevention and treatment of CAD at the patient level, stratification of the cardiovascular risk using simple method is extremely important. Cardiovascular risk screening will have a relevant implication for decision making in early referral and healthcare resource allocation .
What is the aim of the project?
This research aims to improve the validity of the CHA2DS2-VASc score by including new major risk factor of CAD which are Hyperlipidemia (H), Smoking (S) and Family history of CAD (F) and compare it with the previous CHADS2 and CHA2DS2-VASc score to predict severe CAD in the patients.
What techniques and methods are used?
Clinical findings, 12-lead electrocardiogram, and echocardiographic examination were performed based on the American Society of Echocardiography guidelines . The standard laboratory was performed to measure fasting blood glucose, total cholesterol, and renal function tests from the blood samples . CHA2DS2 score was calculated by adding 1 point for the presence of chronic heart failure, age >75 years, DM and hypertension by assigning 2 points for the history of stroke or TIA. In the CHA2DS2-VASc score, age 65-74 was assigned for 1 point (A) and age>75 years (A2) was assigned for 2 points. The CHA2DS2-VASc-HSF score put 1 point for the finding of Hyperlipidemia (H), Smoking (S) and family history of the cardiac disease (F).
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
- Data collection from the medical record into Excel files - Rotation in the Cardiovascular Centre of Soetomo General Hospital, in the rotation, student is expected to learn about cardiology cases and collecting useful data - Data analysis trained by medical resident - Paper writing, review and grammar correction - Opportunity to publish paper together
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Small group discussion Basic cardiology research: Head of Study Program, Cardiology Dept. Andrianto. M.D Techinical aspect in cardiology research: Cardiology resident
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will have the opportunity to present the results together with the supervisor at a conference
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Excellent english writing skill Basic data analysis Grammar correctin
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system - Students in biomedical fields
- Andrianto; Alfarabi; M. J.; Semita; I. G. P. G.; Lathifah; R.; Shonafi; K. A.; & Jovie; B. (n.d.). Validity of CHA 2 DS 2 -VASc-HSF as a Novel Independent Predictor for the Severe Coronary Artery Disease.
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