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Polycystic Ovary Syndrome in Women of Childbearing Age with Metabolic Syndrome in Peri-urban and Urban Area of Cochabamba City.
Bolivia (IFMSA Bolivia) - Universidad de San Simon, Cochabamba
Dr Yercin Mamani Ortiz
Required: English Accepted: Spanish
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Polycystic Ovary Syndrome (PCOS) is the most frequent endocrine disorder among women in Bolivia and occurs in 5 to 10% of the population on reproductive age, with extreme reports that even reach 32%, depending on the population under study. It is the main cause of anovulatory sterility. The polycystic ovarian syndrome does not have a constant hormonal profile. The measurement of circulating hormones with current analytical methods offers very variable results, in many cases difficult to interpret; that is why it has been necessary to resort to some criteria that allow it to be diagnosed. Studies show that more than half of the patients with polycystic ovary syndrome, obese or thin, suffer from insulin resistance, hence the frequency has been found between 50 and 75%. For now, it has been proposed that insulin resistance may be the cause with its own implications.
What is the aim of the project?
Determine the frequency and characteristics of Polycystic Ovary Syndrome (PCOS) in women of childbearing age with Metabolic Syndrome (MS) in peri- urban and urban area of Cochabamba City and its relationship between both syndromes.
What techniques and methods are used?
A prospective, longitudinal study of cases and controls will be carried out, which will include 205 women with Metabolic Syndrome and Polycystic Ovary Syndrome between 18 and 45 years old, from the Outpatient Consultation of the “Nueva Gante” University Health Center, dependent of the Faculty of Medicine of “Mayor de San Simon” University and “Cochabamba” Maternal and Child Hospital. With the information collected, it is expected to have real data for our environment, as well as the particular characteristics of Metabolic Syndrome and Policystic Ovary Syndrome and their relationship that exists between both syndromes in the diagnosis and treatment, to be finally able to elaborate a care protocol, a diagnosis and a treatment of Polycystic Ovary Syndrome / Metabolic Syndrome, to be published and applied in the services of first and second level of healthcare. For the analysis of the data we will use the program IBM SPSS Statistic v-24®; as well as to present and interpret the information of the results of the variables evaluated, using descriptive statistics methods, as well as parametric and non-parametric tests. The verification of the therapeutic efficacy will be compared by means of 2 statistical tests: 1) Student test for independent samples with the group data, at the beginning and at the end of the trial; 2) Students T test for related samples, for the initial and final data of each muscle group. An analysis with Chi square (X2) will also be carried out for each of the nominal variables, such as the risk factors and collateral effects evaluated, to verify the intra-group and intergroup differences.
What is the role of the student?
- If the project is clinical
- the student will take active part in the clinical examination
- If the project is clinical
- the student will be allowed to work with patients
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
- To do some medical history of selected patients interrogating some patients. If the student does not speak English a member of the team will help with the translation. - To do some clinical examination in patients under supervision. (vital signs, blood pressure, weight, anthropometric measurements). - To collect data of the frequency and characteristics of the selected patients. - To collaborate with the analysis of data and the results. For the analysis of the data, the IBM SPSS Statistic v-24 program will be used; 2 statistical tests will be used: Students T test and a Chi square test (X2) that will be previously teach to the student. - To participate in the elaboration of some diagnosis and a care protocol.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Training will be provided prior to project participation by expert personnel in the area
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report - The student’s name will be mentioned in a future publication
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
To know how to take the vital signs and do some basic clinical examination. To have good patient medical interaction. If the student does not speak English a member of the team will help with the translation.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
- 1. Iwata Margareth Chiharu; Porquere Livia; Sorpreso Isabel C. Espósito; Baracat Edmund C.; Soares Júnior José Maria. Association of Oral Contraceptive and Metformin did not Improve Insulin Resistance in Women with Polycystic Ovary Syndrome. Rev. Assoc. Med. Bras. June 2015 [cited 2018 Mar 21] ; 61( 3 ): 215-219.
- 2. Kosmala; W.; O'Moore-Sullivan; T.M.; Plaksej; R. y col. Subclinical impairment of left ventricular function in young obese women: contributions of polycystic ovary disease and insulin resistance. J Clin Endocrinol Metab 93:3748-54; 2008.
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