Projects
Name
Evaluation of Optic Nerve Head by Optical Coherence Tomography in Children with Papilledema or Pseudopapilledema
University
Turkey (TurkMSIC) - Ufuk University, Ankara
Domain
Ophtalmology
Departement
Department of Ophthalmology, Ufuk University Faculty of Medicine, Kizilirmak,Ufuk University Street No:2, 06510, Ankara/Turkey
Head
Assoc. Prof. Pinar A.Ozer
Tutor
Assoc. Prof. Pinar A.Ozer
Languages
Turkish, English
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No No No No No No Yes No No No No
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Papilledema is the swelling of the optic nerve as it enters the back of the eye due to raised intracranial pressure. Optic nerves connect the back of each eyeball and its retina to the brain. Between the brain and the eye, the optic nerve is surrounded with cerebral spinal fluid. Even slight increases in the pressure of this fluid which is due to swelling of the brain might compress the optic nerve. When this nerve is exposed to high pressure, or when it develops inflammation on its own, it can bulge into the back wall of the eyeball, causing papilledema. Some important causes of papilledema are brain tumors, brain infections and head injuries. Besides papilledema might improve as a side effect of taking or stopping some medications. Also, papilledema may cause optic atrophy and permanent vision loss over time. This project involves children with headache or asymptomatic children who are diagnosed with the optic nerve swelling on fundoscopy. (Fundoscopy is an examination that uses a magnifying lens and a light to check the fundus of the eye (back of the inside of the eye, including the retina and optic nerve).) Spectral domain optical coherence tomography (SD-OCT) technique will be used to differentiate the optic nerve head findings in these cases. Also in Turkey Turkish Society of Ophthalmology (TOD) Medical Contact Lens Unit Hikmet Kandemir and Dr.Hikmet Ozcetin secretariat was founded in 1984.Scientific studies have organized national and international meetings and made very valuable contributions to the development of contact lens science in our country.
What is the aim of the project?
To establish the clinical and methodological rules in order to use Optical Coherence Tomography-optic nerve head examination in cases with true or pseudopapilledema after fundoscopical examination.
What techniques and methods are used?
-SD-OCT (Spectral domain optical coherence) technique will be used. -Spectral domain optical coherence tomography (SD-OCT) technique is a different type of OCT (Optical coherence tomography uses light waves to take cross-section pictures of your retina.) which is an interferometric technique that provides depth-resolved tissue structure information encoded in the magnitude and delay of the back-scattered light. -Every subject will be evaluated by OCT-optic nerve head examination and routine fundoscopy as a part of extended neuro ophthalmological evaluation. (Fundoscopy is an examination that uses a magnifying lens and a light to check the fundus of the eye (back of the inside of the eye, including the retina and optic nerve) -Statistical Package for the Social Sciences (SPSS) 26, statistical analysis, data management (case selection, file reshaping, creating derived data) and data documentation (a metadata dictionary is stored in the datafile) are features of the base software.
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- If the project is clinical
- the student will be allowed to work with patients
- The tasks of the student will be performed on his/her own
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The following tasks are expected to be accomplished by the student: -The student should grasp the basics of OCT (Optical coherence tomography uses light waves to take cross-section pictures of your retina.) which is an interferometric technique that provides depth-resolved tissue structure information encoded in the magnitude and delay of the back-scattered light. -He/she may help data record and data analysis by Statistical Package for the Social Sciences (SPSS) 26, statistical analysis, data management (case selection, file reshaping, creating derived data) and data documentation (a metadata dictionary is stored in the datafile) are features of the base software. -Learning Fundoscopy is an examination that uses a magnifying lens and a light to check the fundus of the eye (back of the inside of the eye, including the retina and optic nerve)
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
There are many different subjects open for understanding methods. The subject will be taught once per week by tutor Assoc Dr.Pinar A.Ozer depending on the availability. -SD-OCT (Spectral domain optical coherence) technique procedure which is an interferometric technique that provides depth-resolved tissue structure information encoded in the magnitude and delay of the back-scattered light. -Explaining data management (case selection, file reshaping, creating derived data) by using Statistical Package for the Social Sciences (SPSS) -Describing nerve head examination and routine fundoscopy as a part of extended neuro ophthalmological evaluation.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
No specific skills are required.
Are there any legal limitations in the student’s involvement
No
Hours
6
Type of students accepted
This project accepts:
- Medical students
Articles
- Indian J Ophthalmol. 2014 Dec; 62(12): 1146–1151. doi: 10.4103/0301-4738.149136 PMCID: PMC4313495 PMID: 25579359 Optical coherence tomography in papilledema and pseudopapilledema with and without optic nerve head drusen Shikha Talwar Bassi; Kuppuswamy Parthasarthy Mohana