Projects
Name
[Tunis] Study of the clinical and non-clinical aspects of post tuberculous lung function impairment among known patients in a tertiary hospital in Tunisia and the investigation of the risk factors and the sequelae of the disease.
University
Tunisia (ASSOCIA-MED) - University of Tunis El-Manar/Faculty of Medecine of Tunis, Tunis
Domain
Pneumology
Departement
Pneumology department. Rabta hospital. Jbel Lakhdar Street, La Rabta Jebbari,1007. Tunis, Tunisia.
Head
Dr Samira MERAI
Tutor
Theory: Dr Abir HEDHLI, Dr Sana CHEIKH ROUHOU ; Research: Dr Samira MERAI, Dr Meriem MJID, Dr Sonia TOUJANI, Dr Abir HEDHLI ; Fieldwork:Dr Samira MERAI, Dr Meriem MJID, Dr Sonia TOUJANI, Dr Abir HEDHLI
Languages
Required: English Accepted: French, Arabic
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No No No No No Yes Yes No No No No
Type of Research Project
- Global Action Project (GAP)
What is the background of the project?
Tuberculosis (TB) remains a major health problem worldwide. It is responsible for ill health among millions of people each year [1]. With an incidence of 31 cases per 100,000 inhabitants, Tunisia is a country with an intermediate TB burden that led to the implementation of a National TB Control Program[1]. Despite microbiological recovery is observed in the majority of pulmonary TB patients, more than half of them experience lung sequelae and pulmonary impairment which have been shown to also contributeto TB burden and which could lead to chronic respiratory failure [2-5]. Measuring the negative health impacts of these sequelae is an important component to determining the burden of TB, a disease in which control efforts are largely publicly funded. Unfortunately, few are known about lung function impairment after pulmonary TB in Tunisian population.
What is the aim of the project?
*
What techniques and methods are used?
The student will have to interpret and analyze relevant clinical data for the research topic. The student will also have to prepare a pre-established form to include patient data. During the research period, the student will have to: 1. Collect of data patient: sociodemographic data, clinical data, risk factor of TB, extension of initial TB lesions, bacteriological findings, TB treatment (molecule, duration of treatment …), outcome of TB (complication, side effects, compliance to treatment) 2. Interpret chest x-rays according to international classification of TB sequaele 3. Practice and interpret spirometry: the student will have to learn and to apply the recommendations of good practice of spirometry.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
1. Collection of patient data by an Anamnesis: sociodemographic data, clinical data, risk factor of TB, extension of initial TB lesions, bacteriological findings, TB treatment (molecule, duration of treatment …), outcome of TB (complication, side effects, compliance to treatment, …) The Anamnesis can be performed by the student in Arabic or French. If the student does not speak the language, the tutor will assist him during the procedure by providing translation. 2. Interpretation of chest x-rays 3. Practice and interpretation of spirometry 4. Bibliographic research about the project in general . 5. Data analysis (fill and interpret excel tables) by classifying the patients depending sociodemographic data, clinical data, risk factor of TB, extension of initial TB lesions, bacteriological findings, TB treatment etc ...
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Yes, lectures and courses
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster
- The student will prepare a presentation
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
No specific skills required
Are there any legal limitations in the student’s involvement
No
Hours
7
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
Articles
- 1. World Health Organization. Global tuberculosis report 2016. Geneva: WHO; 2016.
- 2. Pasipanodya JG et al. Pulmonary impairment after tuberculosis and its contribution to TB burden. BMC Public Health. 2010;19;10:259.
- 3. Mbatchou Ngahane BH. Post-tuberculous lung function impairment in a tuberculosis reference clinic in Cameroon. Respir Med. 2016;114:67-71.
- 5. Chronic airflow obstruction syndrome due to pulmonary tuberculosis treated with directly observed therapy--a serious changes in lung function. Med Arh. 2011;65(5):265-9.
- 4. Amaral AF et al. Tuberculosis associates with both airflow obstruction and low lung function: BOLD results. Eur Respir J. 2015 Oct;46(4):1104-12.
- 6. Standardisation of spirometry. Eur Respir J 2005; 26: 319–38.