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(Oradea) Immune hematology status, the blood groups (majors and minor) distribution in blood donors pool in Bihor county, Romania
Romania (FASMR) - University of Oradea - Faculty of Medicine and Pharmacy, Oradea
Immunology Department, Faculty of Medicine and Pharmacy, University of Oradea, Romania
Assistant Professor Olivia Ligia BURTA
Assistant Professor Olivia Ligia BURTA
Type of Research Project
- Basic science
What is the background of the project?
Transfusion medicine is a particular therapy requiring a lot of conditions to be fulfilled, one of them being compatibility donor-recipient from the immune-hematology point of view. The large variety among blood donors pool, of red blood cells antigens, for both majors and minor groups, is a permanent challenge for reducing the “residual risk of transfusion”, mainly when the patient is a multiple transfused one, or at the onset of hematologic pathology, or emergency clinical situations (severe trauma, collective accidents). One of the most efficient way the patient to be transfused in due time, with the best blood component (mainly in case of rare groups), is to have a detailed view of the blood donors pool, according to gender, age, blood donor category.
What is the aim of the project?
The aim of the study, is to build a blood groups catalog (covering major and minor blood groups) along with the immune status (irregular antibodies) in blood donors’ pool. The project is a pilot one, being able further to be applied to some other Romanian regions, to get finally a national image.
What techniques and methods are used?
The techniques used in this project are mixed: the practical part and the documentation part. The practical part is ruled on immune-hematology lab using microscope and performing the classical blood tests. The documentation part will be done, by evaluating, recording the main aspects, from donors files. The data collection will include clinical and paraclinical information from the medical history of the subjects, concerning any pathological history. The last steps are the interpretation of the data gathered and conceiving a proper template for the examination. The conclusion will be summarized and will illustrate clearly the results of the study.
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The student will be introduced in immune-hematology domain of interest. The domain has a tremendous importance, when it includes transfusion therapy. The distribution of blood groups antigens/irregular antibodies in blood donors is important to be known by the student in order to cover mainly particular situations when the patient should be treated with rare blood groups/selected blood. Along with practical part, the student will use microscope and will be able to perform, with close surveillance, the classical blood tests, and also, specific tests, in laboratory, with results interpretation. The student will have to prepare the samples for analysis, to read the results and add them in a database. Together with the tutor, the student will realize the statistical analysis of our project data, constantly communicating with the team for a better development of the project. The information about the immune-hematologic status of the blood donor/recipient, will be helpful and applicable for the student’s future career.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Yes, preliminary readings.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster - The student will prepare a presentation - The student will prepare a scientific report - The student will prepare an abstract - The student’s name will be mentioned in a future publication
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
To know how to work in Excel and PowerPoint Subjects passed: Immunology
Are there any legal limitations in the student’s involvement
Contract, confidentiality form.
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
- Prudent M; Tissot JD; Lion N. The 3-phase evolution of stored red blood cells and the clinical trials: an obvious relationship. Blood Transfusion (2017) 15:188. doi: 10.2450/2017.0317-16.
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