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Systemic Vasculitis National Registry
Moldova (ASRM) - State University of Medicine and Pharmacy Nicolae Testemițanu, Chișinău
Department of Internal medicine, Rheumatology and Nephrology
English - required; Romanian, Russian - accepted
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
There is a lack of data regarding the epidemiology of systemic vasculitis in Republic of Moldova, and even in the Eastern Europe. The project implies to build from scratch a systemic vasculitis national registry, in which all patients will be recorded. The registry will allow to describe the epidemiology of various systemic vasculitis, evaluate present and potential functional and severity scales (e.g. BVAS, PVAS, VDI, Five-Factor Score, DEI, EQ-5D etc.) assess their risk factors as well as plan following years financial budget for the diagnosis and management of these patients.
What is the aim of the project?
Build an online database of patients with systemic vasculitis, using various frameworks and software. Interpretation of the collected data.
What techniques and methods are used?
The research project will begin with creating an online database using the framework Ruby on Rails and PostgreSQL. The student must have basic programming skills. After the database is build, patients with systemic vasculitis hospitalized at two rheumatological departments from the country (Republican Clinical Hospital and St. Trinity Municipal Hospital) will be recorded. The examiners will have to do a thorough physical examination, documenting general and specific results (such as weight, height, presence or absence of purpura etc.). The students will follow a predefined form. The form will have to be introduced in the online database. Further visits to the doctor are also going to be recorded in the database. As enough data is collected, data interpretation will be performed, to assess the incidence, prevalence, evolution, complications, risk factors and other epidemiological information regarding vasculitis. The statistical analysis and data interpretation will be accomplished using software such as IBM SPSS. However, if the budget will allow, the researchers will built powerful algorithms for an in-depth data analysis using R programming language.
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks of the student will be performed on his/her own
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Collecting data according to a standardized questionnaire; Performing physical examination of the following systems: pulmonary, cardiac, gastrointestinal, renal, osteo-muscular, nervous. Data entry in the electronic vasculitis registry of the clinical and laboratory results; Modify the database according the needs of the registry, using skills in front end and back end programming.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
The student will be handed by the tutor upon arrival a list of textbooks, lectures and courses from which one can study individually the theoretical material.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster - The student will prepare a presentation - The student will prepare a scientific report - The student’s name will be mentioned in a future publication - The student will have the opportunity to present the results together with the supervisor at a conference
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
To perform a thorough clinical examination; To be able to collect data; To know how to record parameters; To know the basic of vasculitis clinical manifestations and management; To be able to analyze statistical data;
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Students in biomedical fields
- Musiał J; Wójcik K. Polish Vasculitis Registry: POLVAS. Polish Arch Intern Med. 2017;127(1):71-72. doi:10.20452/pamw.3920
- Ehlers L; Askling J; Bijlsma HW; et al. 2018 EULAR recommendations for a core data set to support observational research and clinical care in giant cell arteritis. Ann Rheum Dis. March 2019:annrheumdis-2018-214755. doi:10.1136/annrheumdis-2018-214755
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