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Validation of the bioelectrical impedance analysis (BIA) for prediction of fat mass in healthy men between 18 and 24 years of age in Manizales.
Colombia (ASCEMCOL) - Universidad de Caldas, Manizales
Biophysics and Medical Physics
Faculty of science for health – University of Caldas Avenue 25 # 48 57, Manizales, Caldas, Colombia
Carlos Augusto Gonzalez Correa
Carlos Augusto Gonzalez Correa; Oleyda Tapasco Tapasco
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
The determination of the corporal composition, especially the fat mass, is one of the most used parameters to evaluate the health risks, the nutritional state and the answer to the medical treatments. There are several techniques to make this determination, but most are expensive, not portable, require highly qualified personnel and are used only at the level of research laboratories. A relatively new, low-cost, non-invasive and easy-to-use technique is known as Bioelectrical impedance Analysis (BIA) that measures the electrical resistance of the individual and this value is included in a formula used to determine the percentage of fat, which indicates the nutritional status (malnutrition or obesity).The formulas vary from one population to another, therefore, for the method to be reliable, it is necessary to develop the formulas for each population, through measurements with samples of the population. To obtain the formulas, the BIA results must be correlated with the results obtained with the gold standard to evaluate the fat mass: hydrodensitometry (or underwater weighing).
What is the aim of the project?
The purpose of this project is to develop and validate the formulas for the use of the Biolectrical impedance Analysis (BIA) in healthy men aged 18-24 years in Manizales, comparing the values of fat mass obtained in the measurements by bioelectrical impedance with those obtained by the gold standard (hydrodensitometry)
What techniques and methods are used?
1. Selection of a sample of the population, 80 volunteer men. Forty individuals will be randomly selected as a validation sample and 40 for cross validation, that is, once the formula is obtained, their values will be used to correlate them with hydrodensitometry. 2. Before including people, they will be examined to assess if there are any conditions that could invalidate the study. Everyone will sign an informed consent. 3. Record the data of each person: age, sex, height, skin folds, weight in the air, weight in the water, residual lung volume, electrical resistance, reactance and impedance. 4. With the above information, the body composition of each individual (% body fat) will be established by two methods: anthropometry and hydrodensitometry. 5. The next step is to establish the predictive value of each variable, which is achieved through a statistical procedure known as multiple step regression analysis through a computer program such as SPSS.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The student must make a complete evaluation of the patient that includes vital signs, dynamometry, anthropometry (weight, height, abdominal circumference) and perform a Bioelectrical Impedance Analysis (BIA) with a medical body composition analyzer. Additionally, the student must collect and tabulate the data for analysis.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
The student should review the bibliography assigned by the tutor and attend the weekly session of the research group, where eventually the student should present a review of a topic (article or project). During the internship there will be two courses: 1) Bibliographic search 2) bases and clinical applications of the bioelectrical impedance
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation - The student’s name will be mentioned in a future publication - The student will have the opportunity to present the results together with the supervisor at a conference
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Communication skills, study skills, commitment to research, basic knowledge in general semiology.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Students in biomedical fields
- Gonzalez-Correa CA. Clinical applications of electrical impedance spectroscopy. In: Simini F; Bertemes-Filho P; editors. Bioimpedance in Biomedical Applications and Research.Springer; Cham; 2018. p. 187-218.
- Gonzalez-Correa CH. Body Composition by Bioelectrical Impedance Analysis. In: Simini F; Bertemes-Filho P; editors. Bioimpedance in Biomedical Applications and Research. Springer;Cham; 2018. p. 219-241.
- Gonzalez-correa CA; Mulett-vásquez E; Miranda DA; Gonzalez-correa CH. The colon revisited or the key to wellness ; health and disease q. Med Hypotheses [Internet]. 2017;108:133–43.
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