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INVESTIGATION OF BIRTH DEFECTS AND INJURIES AND THEIR PREVENTIVE MEASURES
Ghana (FGMSA) - School Of Medical Sciences, KNUST
Prof Anthony Sam
Prof. Daniel Ansong, Mr. Nicholas Mensah
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Birth defects (BD) are disorders or defects that occur in the womb as baby develops and birth injuries happen during or right after birth. Newborn deaths in Ghana stand at 28-30 per thousand live births. Infection, Premature babies and Birth Asphyxia are the main causes of new born mortality. BD and Birth Injury (BI) are also important causes of morbidity and mortality in developing countries however the burden of these two causes of neonatal morbidity are not well documented in Ghana. The causes of most major birth defects remain unknown.In recent times, evidence for associations between known risk factors, such as maternal diabetes, genetics, food pattern of mothers and BD continues to grow, the exact causes of most of these defects remain unknown. A specific cause still cannot be determined for most BD highlighting the persistent gaps in knowledge about birth defects and the challenge of preventing them. Our project aims to establish the relationship between the occurrence of these birth defects and the known risk factors as well as determine some unknown factors by analyzing common characteristics data collected share. So far, 2018 a BD and BI surveillance was established in Komfo Anokye Teaching Hospital (MBU). We intend to use this data and data we are currently collecting for this purpose. This would go a long way to educate us on how to reduce some preventable birth defects
What is the aim of the project?
●This study aims to identify the defects and abnormalities that are likely to occur in childbirth and find it's preventive measures ●Specific objectives ●1. To determine the birth defects prevalent among the study population ●2. To identify the risk factors that predispose babies to these birth defects 3. To put in place preventive measures and to sensitize mothers adequately
What techniques and methods are used?
1. Sampling and data collection which would include administration of a structured questionnaire to collect demographic and clinical information. This would be mostly done in the Komfo Anokye Teaching hospital. This project consists mostly of non-laboratory aspects. 2.Analyzing of the data collected. Inferential quantitative analysis technique would be used by exporting data (which would include; the age characteristics, marital status, mode of delivery, and drugs taken by the mother recently before and during the pregnancy, nutritional history, any underlying conditions along with other risk factors) using Stata software where shared data characteristics are correlated with one another to determine occurrences of known and unknown risk factors 3.Treatment and Evaluation to see the significance of data (by way of common characteristics shared in mothers whose babies have some defects) collected which would be done by research electronic date capture software
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Join sample collection exercise: this is ongoing and if the student arrives while this is still being carried out, then the student can join the team to the various health facilities and be part of the recruitment team. This will involve explaining the Study to potential participants and obtaining written informed consent then administering the questionnaire Student would be involved in the data entry into Research electronic data capture software and data analysis with Stata software. The data analysis would look at the occurrence of shared prenatal characteristics such as maternal diabetes, nutritional history and family history among specific birth defects using inferential quantitative data analysis. The student will be allowed in the data room, to help with data entry, the analysis and the evaluation of the data. . A number of the natives here, speak English hence communication would not be a barrier here.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
No specific skills are required
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
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