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Epidemiological and clinikal features in patients with sexually transmitted disease in Sverdlovsk Region
Russian Federation (HCCM Russia) - Ural State Medical Academy, Ekaterinburg
Department of Dermatoveneorology and Life Safty
Ufimtseva M.A. MD
Ufimceva M.A., Simonova N.V., Savchenko N.V., Mylnikova E.S., Komarov A.A.
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
Sexually transmitted diseases are very common in our days and the incidence of syphilis has increased in the last years. Without treatment, the disease develops into different clinical stages, being able to present cardiovascular or irreversible neurological complications after a number of years. There is a big amount of patients with neurosyphilis. Students have the opportunity to engage in the review papers which systematize the latest news from the specific issue of Venerology. The project also allows the creation of case reports concerning STI patients. Participation in the project approximate to clinical and lab work. Every step will be to supervised by tutors.
What is the aim of the project?
The purpose of the project is to prepare a case report(s) with basis on statistical data analysis (using the venereology reporting forms established in the Sverdlovsk region) and profound literature review.
What techniques and methods are used?
Literature review and statistical data analysis for the first step. Clinical methods: Physical examination of patients in dermatovenereologic dispensary and choosing unusual and rare clinical cases Other methods are also available for differential diagnosing: bacteriological examination, microscopy, Polymerase Chain Reaction (PCR), serology to prove the diagnosing and verification. Preparing the Case Report(s) with oral presentation.
What is the role of the student?
- The tasks of the student will be performed on his/her own
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
● Statistical data analysis (using the venereology reporting forms established in the Sverdlovsk region) ● Physical examination of patients in the dermatovenerologic dispensary (during outpatient reception with a dermatologist) ● Literature review on the research topic (using PubMed, MEDLINE, Embase, e-library, Google Scholar databases) ● Native microscopy during the patient examination (working in laboratory in dermatovenerologic dispensary) ● Polymerase Chain Reaction (working in laboratory in dermatovenerologic dispensary) ● Serology methods ELISA, treponema pallidum hemagglutionation test, IFA, Western blot analysis (working in laboratory in dermatovenerologic dispensary) ● Bacteriological examination of native samples (working in laboratory in dermatovenerologic dispensary). Preparing scientific report with presentation of patient with syphilis.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
1st lection – Syphilis in our days 2nd lection – Statistical reporting in Russia. Also video materials for self-education will be provided.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation - The student will prepare a scientific report - The student’s name will be mentioned in a future publication - The student will have the opportunity to present the results together with the supervisor at a conference
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
- basic knowledge of microbiology, dermatology, venerology, urology, gynecology - literary review skill. Subjects passed: microbiology, gynecology, urology. Previous experience with: working with literature databases as PubMed, MEDLINE, Embase, e-library, Google Scholar.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system - Students in biomedical fields
- https://www.ncbi.nlm.nih.gov/pubmed/30624362 OʼByrne P MacPherson P Kitson C Bourgault A.J Consideration of sexually transmitted infections in the differential diagnosis: Case studies. Am Assoc Nurse Pract. 2019 Jan;31(1):65-71. doi:10.1097/JXX.0000000000000103
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607913/ Mena Lora AJ; Braniecki M; Nasir A; Brito M. The great impostor: Lues maligna in an HIV-infected male. SAGE Open Med Case Rep. 2017;5:2050313X17731050. Published 2017 Sep 19. doi:10.1177/2050313X17731050
- https://www.nejm.org/doi/10.1056/NEJMicm1804118?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dwww.ncbi.nlm.nih.gov H. Holzgreve. (2019) „Mottenfraß“ am Kopf bei syphilitischer Alopezie. MMW - Fortschritte der Medizin 161:2; 35-35.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103325/ Eyer-Silva WA; Souza VPB; Silva GARD; et al. Secondary syphilis presenting as a corymbiform syphilide: case report and review. Rev Inst Med Trop Sao Paulo. 2018;60:e40. Published 2018 Aug 20. doi:10.1590/S1678-9946201860040
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