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Basic Attention and Non-Melanoma Neoplasms: a multidisciplinar study
Brazil (IFMSA-Brazil) - Universidade Federal de Rondonia, Porto Velho
Laboratório de Genética Humana
Andonai Krauze de França
Andonai Krauze de França
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
Skin cancer, in the last decades, has acquired special importance due to its increasing incidence. According to the National Institute of Cancer estimates in 2016 the most common type of cancer in both sexes will be non-melanoma skin cancer. Considering that each lesion is unique, adequate treatment should allow a reduction of the high indexes of locoregional and systemic dissemination, as well as increase the survival of the patients, being essential the realization of the early diagnosis. This research aims to verify the genetic bases related to Non-Melanoma Cutaneous Cancer, its rare variants and associated syndromes, to carry out a survey of the clinical history of its patients and to map the path of the same ones within the different levels of health care. This will be done by means of a quantitative study of a descriptive approach where the histological examination and molecular analysis of the biological samples of patients with suspected Non-Melanoma Skin Cancer, its rare variants or associated syndromes will be done.
What is the aim of the project?
To verify the genetic bases related to Non-Melanoma Cutaneous Cancer - NMCC, its rare variants and associated syndromes, and to map the path of patients within the different levels of health care.
What techniques and methods are used?
Data collection with posterior analysis; interview and genetic monitoring with patients.
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The student is expected to understand how certain skin cancers such as non-melanoma skin cancers and others, affects the deoxyribonucleic acid (DNA) and to understand how to determine the mutation of the observed alleles for accurate diagnosis. In addition, she/he will have a participation in the construction to map the path of patients within the different levels of health care. Finally,in the end of the exchange the student will able to understand the psychosocial aspects involved in patient care.Moreover, they can see the disease implications in the the patient’s family.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
The student is expected to understand how certain skin cancers such as non-melanoma skin cancers and others, affects the deoxyribonucleic acid (DNA) and to understand how to determine the mutation of the observed alleles for accurate diagnosis. In addition to the participation in the construction to map the path of patients within the different levels of health care. Finally, to understand the psychosocial aspects involved in patient care and its implications within the family.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report - The student will prepare an abstract
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
The student need to know the molecular biology techniques.Futhermore, she/he need to be empathy, initiative, communication skills and scientific and investigative spirit. Subjects passed: Molecular biology and/or genetics - Certificated in English
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Students in biomedical fields - Dental medicine students (IADS members)
- Vasiliki Nikolaou; Alexander J. Stratigos and Hensin Tsao. Hereditary Nonmelanoma Skin Cancer. NIH Public Access; 2012.
- MARTINEZ; Marcos Antonio Rodrigues et al. Molecular genetics of non-melanoma skin cancer. Anais Brasileiros de Dermatologia; v. 81; n. 5; p. 405-419; 2006.
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