PREMOM II: a prenatal remote monitoring follow-up program for women with gestational hypertensive disorders.
Belgium (BeMSA) - UHasselt, Hasselt
Hospital Oost-Limburg
Prof. Dr. Piet Stinissen
Prof. Dr. Wilfried Gyselaers, Dr. Dorien Lanssens
English, Dutch
4 weeks
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No No No No No Yes Yes No No No No
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?

Worldwide, 5 to 8% of all pregnant women develops gestational hypertensive disorders (GHD). This means that yearly ca. 3000 of the 64000 pregnancies in Flanders are complicated with this disorder.
Although randomized controlled trials among pregnant women at risk for the development of GHD have shown that appropriate blood pressure measurements are an important aspect of the prenatal care, implementation of a standardized care process that enables these blood pressure measurements to be adequately monitored, has not yet been introduced in clinical practice.
A care program that could make the most of these blood pressure measurements, is complementing prenatal care programs with telemonitoring (TM). TM is a complete care process that included information exchange between caregivers in the hospital and the patient at home. Pilotstudies showed that TM contribute to better follow-up eventuating in GHD prevention when compared to conventional care (CC).

What is the aim of the project?
Performing a prospective, multicenter, randomized controlled trial (RCT) in which TM is compared to CC.
What techniques and methods are used?

We will compare 3 groups, to women at risk for GHD will be randomly assigned:
- Telemonitoring group
- Patient self-measurement group
- Conventional care group

These groups will be compared for:
- The prenatal follow-up
- Delivery outcomes
- Costs for the health care services
- Contributors to added value of TM
- Perceptions/satisfaction

This is a multicenter study: Ziekenhuis Oost Limburg (Genk), UZLeuven (Leuven), UZA (Antwerpen), Sint Jan & Sint Lucas (Brugge), UHasselt are participating. The following steps will be done:
- Set up and conduct a randomized controlled trial
- Inclusion of a patient self-monitoring group
- Detailed registration of the interventions
- Cost-analysis and willingness-to-pay analysis

What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?

- Be involved in the screenings program to detect the risk for GHD
- Help with the inclusion of the patients in the TM program
- Follow-up of the patients included in the TM program
- Site visits of which are involved in the project
- Help with statistical analysis (analyses with demographic data and preliminary analyses of the gestational outcomes): (paired/unpaired) t-test, chi square, etc
- Contact with obstetricians and other caregivers to guide women in high risk pregnancies

Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?

- Basic statistical knowledge (analyses with demographic data and preliminary analyses of the gestational outcomes): (paired/unpaired) t-test, chi square, etc
- Empathic and social ability to talk with women with a high risk pregnancy

The student must have a bachelor's degree.

Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
- Students in biomedical fields
- Lanssens D et al.; Effectiveness of Telemonitoring in Obstetrics: Scoping Review. J Med Internet Res 2017;19(9):e327; doi: 10.2196/jmir.7266.
- Lanssens D et al.; Remote Monitoring of Hypertension Diseases in Pregnancy: A Pilot Study. JMIR Mhealth Uhealth 2017;5(3):e25; doi: 10.2196/mhealth.6552
- Smeets; Christophe J.P. et al.; Detection of subclinical transient fluid accumulation during pregnancy in a patient with an implantable cardioverter defibrillator and OptiVol® fluid monitoring algorithm; International Journal of Cardiology; Volume 214; 163-165; doi: 10.1016/j.ijcard.2016.03.121.
- Lanssens; Dorien et al. (2018). The impact of a remote monitoring program on the prenatal follow-up of women with gestational hypertensive disorders. European Journal of Obstetrics & Gynecology and Reproductive Biology. 223; doi: 10.1016/j.ejogrb.2018.02.015.
- Lanssens D et al.; Prenatal Remote Monitoring of Women With Gestational Hypertensive Diseases: Cost Analysis; J Med Internet Res 2018;20(3):e102; doi: 10.2196/jmir.9552.