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Caesarian Section Surgical Site Infections (SSI) in a tertiary hospital of Sierra Leone: a case-control study
Sierra Leone (SLEMSA) - College of Medicine and Allied Health Sciences University of Sierra Leone, Freetown
Doctors with Africa (CUAMM), Department of Obstetrics and Gynaecology
Dr. Enzo Pisani
Francesco Di Gennaro; Claudia Marotta
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Surgical site infections (SSI) are a significant cause of post-surgical morbidity and mortality and can be an indicator of surgical quality. SSI are the most common nosocomial infection in sub-Saharan Africa (SSA). Risk factors for post-operative SSI are multi-factorial and include the type of surgical procedure, the length of operation, and the patient’s prior co-morbidities. SSI rate, determinants and outcome of Princess Christian Maternity Hospital (PCMH), Freetown is not known and studied, but a better understating could be important to address hospital improvement strategy.
What is the aim of the project?
To understand determinants, incidence and outcome of SSI in post-CS in a Maternity hospital of Freetown.
What techniques and methods are used?
A case control study has been designed and is now ongoing. The student will be involved in the data collection phase. Data collection is performed with a form using both the patient’s chart and through a deep clinical assessment of all cases of SSI post CS and 3 controls for each cases. Variables will include information about the pregnancy, the operation, the treatment of the SSI. Data collection will last at least 5 months. Data will be entered in an excel sheet and further analyzed with STATA 13.0.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
A brief presentation of the scientific research methodology will be performed for the student. The student will be involved in the data collection: each morning an Infectious disease doctor does a round in each hospital ward to detect and enroll all the new SSI cases. For each case also 3 controls are enrolled. The patient’s condition then will be checked each single day until the discharge. Also a search of the literature on the specific topic of investigation through the main databases will be performed by the student after a proper training in order to learn how to conduct the background step of every scientific research project.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
A brief presentation of the scientific research methodology will be performed for the student. On the job training will follow on: data collection, data quality, data entry, literature search, SSI clinic and management.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Motivation. No special Knowledge required
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
- Allegranzi B; Bischoff P; de Jonge S; et al. New WHO recommendations on preoperative measures for surgical site infection prevention: an evidence-based global perspective .Lancet Infect Dis 2016; published online Nov 2. http://dx.doi. org/10.1016/S1473-3099(16)30398-X.
- Acosta CD; Knight M. Sepsis and maternal mortality. Curr Opin Obstet Gynecol. 2013;25(2):109–16.; Barton JR; Sibai BM. Severe sepsis and septic shock in pregnancy. Obste Gynecol. 2012;120(3):689–706.
- . Acosta CD; Knight M; Lee HC; Kurinczuk JJ; Gould JB; Lyndon A. The continuum of maternal sepsis severity: incidence and risk factors in a population-based cohort study. PLoS One. 2013;8(7):e67175.)
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