Hemathologic malignancy: from morphology to molecular biology-everlasting chellange
Bosnia and Hrezegovina (BoHeMSA) - Univerity of Tuzla, Tuzla
Pathology Department, University Clinical Center
Prof. dr. Ermina Iljazović
Prof. dr. Ermina Iljazović
English, Bosnian, Croatian, Serbian
4 weeks
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No No No No No Yes No No No No No
Type of Research Project
- Basic science
What is the background of the project?
Hemathologic malignancy are one of the most common, particularly in the childhood. The many stages of normal hematopoietic differentiation give rise to a number of biologically and clinically distinct cancers. Hematologic malignancies have historically been at the vanguard among cancers in the use of genetic analyses for diagnosis, classification, prognostication, and therapeutic decision-making. Genomic analysis has greatly influenced the diagnosis and clinical management of patients affected by diverse forms of hematologic malignancies. Thanks to new different diagnostic technique particularly molecular one, pathology become a key point in the management, follow up and prognosis of the hematology cancer patients.
What is the aim of the project?
To face the students with and to introduce them in a diversity of hematologic malignancies and all diagnostic steps necessary to establish a right diagnosis.
What techniques and methods are used?
Clinical examination (medical history); bone marrow biopsy, flow cytometry; cytogenetic analysis; molecular PCR(Polymerase chain reaction techniques); microscopic analysis of bone marrow biopsy.
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks of the student will be performed on his/her own
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Discuss clinical features, including differential diagnoses for the various hematologic malignancies. Describe recent advances in diagnostic for the various hematologic malignancies. Define the state-of-the-art for genomic analyses for hematologic malignancies Engage in ongoing exchange of information, ideas and approaches with the people involved in the project to develop a plan, communicate findings and/or evaluate the validity of results.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Introduction seminar about the work process, what we already did and what we will do.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation
- The student will prepare a scientific report
- The student will have the opportunity to present the results together with the supervisor at a conference
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Pathology should be passed.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
- International Classification of Diseases for Oncology. (2000). Geneva: World Health Organization.