Projects
Name
Next generation sequencing in biomedical field
University
Morocco (IFMSA-Morocco), Faculty of Medicine and Pharmacy of Rabat, Rabat
Domain
Biotechnologies and Informatics
Departement
Biothechnology, faculty of medicine Rabat
Head
Azeddine Ibrahimi
Tutor
Azeddine Ibrahimi ; a.ibrahimi@um5s.net.ma
Languages
English, French
Duration
8 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
yes yes yes yes yes No No No yes yes yes yes
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Next generation sequencing in the biomedical field has drastically increased the total number of produced sequence reads per run (in comparison with previous older used technologies) thus allowing for a previously unprecedented view into complex mixtures of RNA and DNA samples. Therefore, we should further develop next generation sequencing tools in the biomedical field so as to improve its reading speed and discover more information on DNA and RNA. And the best way to develop these tools are by studying they applications and the way they work.
What is the aim of the project?
The aim of the project is to develop next generation sequencing in biomedical field through studying its applications.
What techniques and methods are used?
BioInformatics Tools / Molecular Biology Tools (such as DNA Isolation Kits, DNA Ligation Kits, PCR Quick Screening Kits, Molecular Biology Enzymes & Enzymes Antibodies (for DNA and RNA sequencing…)
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Manipulation and mastering the technology of molecular biology tech (the functioning of several molecular biology tools (such as DNA Isolation Kits, DNA Ligation Kits, PCR Quick Screening Kits, Molecular Biology Enzymes & Enzymes Antibodies) and bioinformatics technology, collecting data regarding the performance and the results of the equipment and techniques used, storing said data then analyzing it using SPSS data analysis software.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
YES, lectures delivered by the tutor (history of molecular biology technologies, DNA sequencing techniques…)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic Molecular Biology Tools knowledge
Are there any legal limitations in the student’s involvement
No
Hours
6
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
- Pre-Medical students from the American-British system
- Students in biomedical fields
Articles
- www.medbiotech.ma
- “Next generation sequencing technology: Advances and applications”; H.P.J.Buermans; J.T.den Dunnen. (http://www.sciencedirect.com/science/article/pii/S092544391400180X)
- “The impact of next-generation sequencing on genomics”; Jun Zhang; Rod Chiodini; Ahmed Badr; and Genfa Zhangd. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076108/)
- “Next generation sequencing in clinical medicine: Challenges and lessons for pathology and biomedical informatics”; Rama R. Gullapalli; Ketaki V. Desai; Lucas Santana-Santos; Jeffrey A. Kant; and Michael J. Becich. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519097/)