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Study of properties of causative agents of mycoses and methods of their laboratory diagnosis.
Russia (TaMSA-Tatarstan) - Kazan State Medical University, Kazan
Department of Microbiology Kazan, Tolstogo 6/30
Guzel Shavhatovna Isaeva
Pavel Evgen’evich Gulyaev
Type of Research Project
- Basic science
What is the background of the project?
Nowadays, fungal infections or mycoses cause a wide range of diseases in humans, especially patients with immunosuppression state. Mycoses range in extent from superficial infections involving the outer layer of the stratum corneum of the skin to disseminated infection involving the brain, heart, lungs, liver, spleen, and kidneys. Microscopic fungi cause these infections. Many of this infections shift to chronic forms and cause dangerous complications to that person. However, nowadays, laboratories have modern equipment to provide diagnosis of these diseases and if period of time is short it provides opportunity to avoid complications.
What is the aim of the project?
Our aim will be to study the properties of fungi and such methods of laboratory diagnosis of mycoses as direct examination, DNA hybridization, immunodiffusion.
What techniques and methods are used?
In this project, we will use microscopic and mycological methods of laboratory diagnosis. Using nonculture techniques such as direct examination, DNA hybridization, immunodiffusion that can allow detection and identification of the etiologic fungus or provide immunologic evidence of a specific fungal infection.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The role of the student will be to actively participate in the research project. During the laboratory work the student will be taught basic techniques and able to do it by himself in such method as direct microscopic examination. The primary purpose of a direct microscopic examination (wet mount) is to determine whether or not mold is growing on the surface sampled, and if so, what kinds of molds are present. Except this the student will observe practical experiments using DNA hybridization, immunodiffusion and after these procedures will be highly involved in the analysis of the results.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic knowledge of Microbiology
Are there any legal limitations in the student’s involvement
Student is allowed to this project only after passing of safety techniques.
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system - Students in biomedical fields - Dental medicine students (IADS members)
- Karatygin I.V. Fossil Fungi: The Present State of the Problem. In: Advances in Medical Mycology. Vol. 1. Sergeev Y.V. (ed.). Moscow; All-Russian Natl Acad Mycol; 2007. P. 10-28.
- Sergeev Y.V. Medical Mycology in Russia: Current State and Future Directions. In: Advances in Medical Mycology. Vol. 1. Sergeev Y.V. (ed.). Moscow; All- Russian Natl Acad Mycol; 2007. P. 305-312.
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