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Early detection of psychiatric risk (IPRP - Interdisciplinary Pain Rehabilitation Program protocol)
Universita degli Studi di Bari
Department of Neuroscience
Prof. Alessandro Bertolino
Dott.ssa Ileana Andriola
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Longitudinal study of 36 months with 5 follow-up visits. The main object is to identify biomarker that differentiate individual at risk of mental states (ARMS) who convert to the diagnosis (Schizophrenia of bipolar disorder) from those who do not become ill. The collection of anamnestics, socio-demographics data, clinical, neuropsychological, instrumental (fMRI, Functional Magnetic Resonance Imaging) and genetic evolution will be performed.
What is the aim of the project?
The main object is to identify biomarkers that differentiate people who convert to the diagnosis and people who don't become ill.
What techniques and methods are used?
Anamnestics and socio-demographics data clinical and neuropsychologicalevolutions, instrumental (FMRI) and genetic (blood sampling) evolutions.
What is the role of the student?
- The student will mainly observe
What are the tasks expected to be accomplished by the student?
They have to learn how to administer psychometric and clinical questionnaire (Positive and Negative Syndrome Scale - PANSS; Scale of Assessment of Negative Syndrome – SANS; Brief Psychiatric Rating Scale – BPRS; Young Mania Rating Scale –YMRS; Montgomery-Asberg Depression Rating Scale – MADRS above all, and Structured Clinical Interview for Diagnostic and Statistical Manual of mental disorders - SCID, Comprehensive Assessmentof of At Risk Mental States - CAARMS, (Personal and Social Performance Scale - PSP, Specific Levels of Functioning- SLOF, Social Cognition and Object Relations Scale - SCORS, Global Assessment of Functioning- GAF) and neuropsychological tasks (N- Back either inside and outside the machine – fMRI , Verbal Fluency, Trail making test A -TMT-A, Trail making test B - TMT-B, AX Continuous Performance Task - AX-CPT, Wechsler Memory Scale - WMS, Wisconsin card sorting test - WSCT, Wechsler Adult Intelligence Scale - WAIS above all).
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Seminars and courses
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
The interest in clinical research. Please read “Development and validation of a clinically based risk calculation for the transdiagnostic prediction of psychosis” ; FusarPolietal. SAMA Psychiatry, 2017 May.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
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