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3D printing production of scaffolds for bone regeneration
Portugal ( PorMSIC) - University Beira Interior, Covilha
Orthopaedics and Rehabilitation
Departamento de Ciencias Medicas, Faculdade de Ciencias da Saude, Avenida Infante D. Henrique, 6200-506 Covilha
Professor Luis Manuel Taborda Barata
Professor Ilidio Joaquim Sobreira Correia
Type of Research Project
- Basic science
What is the background of the project?
The limited capacity of bones to fully repair large defects requires the development of new implants. In this context, new approaches have been used to promote bone regeneration and also to avoid the side effects associated with the therapeutics currently used in the clinic. A particularly promising approach for bone regeneration uses 3D printing technologies to produce scaffolds with highly controlled structure and orientation, based on computer-aided design models or medical data that meet the patient needs.
What is the aim of the project?
The aim of this project is to design, produce and characterize new scaffolds by 3D printing for bone regeneration
What techniques and methods are used?
The 3D scaffolds will be produced by rapid prototyping. Scaffolds mechanical properties will be characterized and the biological properties will be evaluated in vitro using osteoblast as model cells.
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The student will produce the 3D scaffolds by rapid prototyping, in a fab@home printer with the supervision of a researcher. Further, the student will be introduced to the in vitro cell culture techniques and will evaluate the scaffold biocompatibility for osteoblast cells. All work will be done with supervision in the beginning so that the student can understand the procedures and learn from observation.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
There will be no theoretical teaching,so it is advisable to read previously the Correia et al. articles in the bone regeneration area.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
No specific skills are needed.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
- R. Fradique; T. R. Correia; S. P. Miguel; K. D. de Sa; D. R. Figueira; A. G. Mendonca; I. J. Correia (2016) Production of new 3D scaffolds for bone tissue regeneration by rapid prototyping. (http://link.springer.com/article/10.1007%2Fs10856- 016-5681- x)
- K. D. de Sa; D. R. Figueira; S. P. Miguel; T. R. Correia; Abilio P. Silva; I. J. Correia (2016) 3D scaffolds coated with nanofibers displaying bactericidal activity for bone tissue applications. (http://www.tandfonline.com/doi/abs/10.1080/00914037.2016.1236338)
- K. D. de Sa; D. R. Figueira; S. P. Miguel; T. R. Correia; Abilio P. Silva; I. J. Correia (2016) 3D Printed scaffolds with bactericidal activity aimed for bone tissue regeneration. (http://www.sciencedirect.com/science/article/pii/S014181301630530X)
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