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LEFT VENTRICULAR FUNCTION IN DIABETIC AND NON-DIABETIC HAEMODIALYSIS PATIENTS( Suez Canal University)
Egypt (IFMSA-Egypt) - Suez Canal University, Suez Canal
Department of Cardiology
Prof. Hesham Hegazy
Dr. Basma osman
Required: English Accepted: Arabic
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
Haemodialysis patients are subjected to increased risk of cardiovascular morbidity and mortality. Patients with end stage renal disease (ESRD) and diabetes have significantly bigger left atrial size, thicker left ventricular walls and higher serum ferritin levels than the patients without diabetes. There is no strong evidence to support the correlation between diabetes and cardiovascular morbidities in end-stage renal disease patients.On the one hand, it is well known that poor appetite and negative energy homeostasis are common in ESRD patients; on the other, that cardiovascular disease is the leading cause of mortality in these patients. We hypothesize that inadequate endogenous ghrelin levels disturb intake desire, causing cardiovascular complications in ESRD patients.
What is the aim of the project?
To improve management of left ventricular systolic and diastolic dysfunction among diabetic and non- diabetic end stage renal disease patients who are maintained on haemodialysis.
What techniques and methods are used?
This is a case control study that will conduct on patients who attended Dialysis units in Suez Canal University and Ismailia General Hospitals. Techniques: Electrocardiogram (ECG) / percentage of Glucose in the blood / Deoxyribonucleotide acid (DNA) extraction,
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Collecting medical history (done under supervision). Performing general and local examination (done under supervision). Collecting blood samples for lab measurements (done under supervision). Collecting the data about echocardiogram and kidney function test and then contributing in giving results (done under supervision). Study and explain the basics of diabetic nephropathy and its complications (done alone).
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Theoretical teaching about history, examination, clinical skills, interpreting lap results in form of lectures and clinical talks. 2-3 lectures per week conducted by tutors mentioned above.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Know how to take medical history and perform a general examination. Interpretation of blood glucose and kidney function test. Interpretation of electrocardiogram and echocardiogram. Previous experience with: Internal Medicine
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system - Students in biomedical fields
- Left ventricular diastolic dysfunction in patients under periodic hemodialytic treatment. Rev Port Cardiol 1999 Sep;18 Suppl 5:V85-8
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