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Network for the research of illnesses by Clostridium difficile in Hospitals Class A (RIECdif).
University of Costa Rica
Laboratory of Biological Trials.
Dra. Sara González Camacho
Dr. Carlos Quesada Gómez
English and Spanish
Type of Research Project
- Basic science
What is the background of the project?
The researchers of the laboratory of investigation in bacteriology anacrobic of the University of Costa Rica ((LIBA-CIET-UCR) have a trajectory of more of 20 years studying the infections produced by anacrobic bacterias. In the last years, and as a consequence of the incresing of the number and severity of associated diarreas to antibiotics in costarican hospitals, the lIba focused their efforts to understand from a molecular perspective the epidemiology of the infections caused by C. Difficile. So it is expected that with this project of networks, it can be followed up to the first planned and it can be consolidated a wide network of work in the subject of illnesses produced by this hospital pathogen that continues having a big relevance in the costarican hospitals
What is the aim of the project?
Nosocromial infections and illnesses produced by C. Difficile are a frequent cause of clinic complications because they extend the stay of the patients in the hospital and they can leave a permanent aftermath and even they can cause death of the affected. The consolidation of a thematic network in the topic of the role of C. Difficile in nosocromial diarreas at national and latin american level. In this way, will materialize a solid network of research, with a base in the University of Costa Rica, that will obtain important contributions in the generation of scientific knowledge which tranference will contribute to improve the understanding, prevention, diagnosis and treatment of the diarreas associated to C. Difficile and it will give an important international projection to the University of Costa Rica.
What techniques and methods are used?
To study the role of Clostridium difficle in clinical picture, the pathogenesis and virulence, the mechanisms of action of toxins, the resistence to antibiotics and it`s sensitivity to antimicrobials, the intestinal inflamation and in general the description of the “autochthonous” or own strains in the costarican hospitals.
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
- To perform the experimental techniques mentioned above. - To analyze and interpret experimental data. - To prepare a scientific report. - To prepare a presentation to the research group.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
1. Yes. Induction in modules for the correct use of laboratory, proper use of the microscope and manipulation of samples.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster - The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Previous experience with: Microscopy basic and basic laboratory techniques. Subjects passed: Physiology, biochemistry, microbiology, parasitology and medical genetics. Third years of medicine and to be able to work in group.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system
- 3. <http://www.ciet.ucr.ac.cr/index.php?option=com_content&view=article&id=58%3Acarlos-quesada-gomez&catid=5&Itemid=14>
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