Comparison of myocardial wall thickness on cardiac computed tomography and magnetic resonance imaging.
Denmark (IMCC) - Copenhagen University, Copenhagen
Cardiac CT Research unit Department of Cardiology Rigshospitalet
Klaus Fuglsang Kofoed, MD, PhD, DMSc
Per Ejlstrup Sigvardsen, MD, PhD-fellow
4 weeks
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No No No No No Yes No No No No No
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Left ventricular hypertrophy is among the best predictors of cardiac mortality and morbidity independent of etiology. Hypertrophy is however not always global – it may be regional, e.g. only in relation to the ventricular septum. Global hypertrophy may be identified by echocardiograms while magnetic resonance imaging (MRI) or cardiac computed tomography (CCT) are required to identify regional hypertrophy. While MRI is currently the gold-standard for evaluating regional thickness no study have shown if a discrepancy exists between MRI or CCT.
What is the aim of the project?
The present study will elucidate whether measures of regional hypertrophy as evaluated by CCT is in accordance with those of MRI through the heart cycle, in a variety of participants ranging from healthy individuals, to patients with ischemic heart disease, valvular heart disease, or patients with cardiomyopathies.
What techniques and methods are used?
Patients undergo both CCT and MRI at Rigshospitalet, Denmark. Measurements of regional left ventricular wall thickness, in addition to chamber dimensions will be performed on CCT as well as MR. The measurements will be performed in accordance with the American Heart Association guidelines for chamber quantification and will be performed on dedicated workstations under close supervision from experienced physicians.
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The student will be responsible for the measuring of regional wall thickness and chamber dimensions on CCT as well as MRI of functional cardiac measurements on CCT and MRI. This will be performed for approximately 100 patients. As outlined in the methods sections this will be performed on dedicated workstations under close supervisions of experienced physicians. The department will offer an introductory course to cardiac-CT chamber quantification. Additionally - the department will offer the student to participate in the preparation of patients undergoing Cardiac-CT - including ECG-analysis and echocardiography - this will done under supervision.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
There will be theoretical teaching provided.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts:
- Medical students