New nutrigenomic approach to investigate the benefits of dairy product consumption on glucose homeostasis
Université Laval
Centre de recherche du CHU de Quebec ? Universite Laval
Claudia Gagnon and Iwona Rudkowska
Sarah Chouinard-Castonguay
4 weeks
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
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Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Epidemiological evidence is accumulating for an inverse association between dairy product intake and type 2 diabetes (T2D) risk. However, dairy product intervention studies report mixed results on insulin sensitivity. Recently, we revealed a gene-diet interaction between dairy intake and glucokinase (GCK) gene on insulin sensitivity (Rudkowska, 2015). These preliminary results indicate that the intake of dairy products may influence glucose-insulin homeostasis in individuals with genetic variations related to T2D.Our in vitro results suggest that dairy nutrients modify expression levels of key genes related to glucose metabolism (Chartrand, 2015). Further, nearly 45% of the French-Canadian population do not meet Canada's Food Guide recommendations of at least 2 portions of dairy products/day (Da Silva, 2014).
What is the aim of the project?
What techniques and methods are used?
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks of the student will be performed on his/her own
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Data analysis
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
See article below
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts:
- Medical students
- Sarah Chouinard-Castonguay; Jessica Vigneault; Genevieve Faucher; S. John Weisnagel; Andre Tchernof; Julie Robitaille. Relation Between Dietary Intakes and Circulating Cytokine Concentrations According to Obesity Status Among Women With Prior Gestational Diabetes. Canadian Journal of Diabetes; 2012.