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Transcription factors as key targets to regulate the selective vulnerability of dopamine neurons
Department of psychiatry and neuronsciences
Yves De Koninck
Type of Research Project
- Basic science
What is the background of the project?
Mitochondrial defects have been recognized as important and well-established contributing factors to the pathogenesis of Parkinson
What is the aim of the project?
What techniques and methods are used?
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks of the student will be performed on his/her own
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Learn fast, calculate dilution, know how to use a pipette, fill a laboratory notebook, manipulate laboratory animals.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
- Doucet-Beaupre H; Gilbert C; Pacelli C; Giguer N; Rioux V; Schaan Profes M; Charest J; Chabrat A; Deng Q; Laguna A; Ericson J; Perlmann T; Ang S-L; Cicchetti F; Parent M; Trudeau L-E; Levesque M. (2016) Lmx1a and Lmx1b actively regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proceedings of the National Academy of Sciences 113 (30); E4387-E4396.
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