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Investigation of Ebstein Barr Virus
Turkey (TurkMSIC) - Hacettepe University, Ankara
Department of Pathology
Gokhan Gedikoglu, MD, Professor of Pathology
Kemal Kosemehmetoglu, MD
Type of Research Project
- Basic science
What is the background of the project?
Oncologic viruses play an important role in the etiology of the cancer. Association of Ebstein Barr Virus (EBV) with leiomyosarcomas in immunocompromised patients, such as HIV (Human Immunodeficiency Virus) infected patients and transplant recipients, is well established. EBV has been demonstrated in most smooth muscle tumors associated with acquired immunodeficiency syndrome and other immunocompromised states This project will be a cohort study of conventional uterine leiomyosarcomas. This project
What is the aim of the project?
What techniques and methods are used?
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
No special skill is demanded. Neverthless we highly require students who are excited about pathology and research.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
- 1- Miettinen M. Smooth muscle tumors of soft tissue and non-uterine viscera: biology and prognosis. Mod Pathol. 2014 Jan;27 Suppl 1:S17-29. doi: 10.1038/modpathol.2013.178.
- 2- Deyrup AT et al; Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients. Am J Surg Pathol.2006 Jan;30(1):75-82.
- 3- Enzinger and Weiss
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