Projects
Name
Innate immunity and tissue remodeling in progressive renal failure.
University
the Netherlands (IFMSA-NL) - University of Groningen, Groningen
Domain
Nephrology
Departement
Dept. Internal Medicine, Div. Nephrology, Lab Experimental nephrology. Groningen University, Groningen, the Netherlands
Head
Dr. J. van den Born. E-mail: j.van.den.born@umcg.nl Phone: +31 50 361 0475
Tutor
PhD student Ryanne Hijmans
Languages
English, Dutch
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
yes yes yes yes yes yes yes yes yes yes yes No
Type of Research Project
- Basic science
What is the background of the project?
In our lab we perform basic and translational research on progressive renal failure both in native and transplanted kidneys. Part of the work is done in rodent models for renal diseases, part is in vitro using renal cell culture models, part is with human materials. The aim is to to understand mechanisms of progressive renal failure and to actively work on interventional therapies. Used techniques: Immunohistochemistry on formalin-fixed, paraffin-embedded and cryopreserved tissues; qRT-PCR, Cell culture, Western blotting, ELISA
What is the aim of the project?
To understand mechanisms of progressive renal failure and to actively work on interventional therapies.
What techniques and methods are used?
Immunohistochemistry on formalin-fixed, paraffin-embedded and cryopreserved tissues; qRT-PCR, Cell culture, Western blotting, ELISA
What is the role of the student?
What are the tasks expected to be accomplished by the student?
The student is expected to participate actively in the research. His/her tasks will mainly consist of analysis in the lab and interpretation of the gathered data. This will be in cooperation with the daily supervisor. The student can also work on his/her outcome for the exchange, as described below.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
1
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
The student needs to have at least some lab experience, so knowing how to handle pipets, how to behave in a research surroundings etc. Besides, proper vaccination against hepatitis B and a declaration of non-MRSA infection is needed. Search PubMed under the name: van den Born J. For example PMID: 26952289, 26445497, 26788523. Specific, most recent articles could be sent upon arrival of the student through contact with the LORE.
Are there any legal limitations in the student’s involvement
No
Hours
8
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
- Pre-Medical students from the American-British system
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