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Initial approach and clinical evaluation in children with seizures of different etiology
Serbia (IFMSA-Serbia) - University of Belgrade, Belgrade
Neurology department, University Children
Associate professor Dragana Bogicevic, MD PhD
Associate professor Dimitrije Nikolic, MD PhD
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
Seizures are one of the most common neurological symptoms, and as such is present in many different neurological or non-neurological diseases and acute conditions. It might be first sign of epilepsy or other diseases of different etiology. Differentiating between first seizure, epilepsy and a non-epileptic event is a challenging clinical exercise for many physicians as it may lead to different therapeutic implications. Those conditions are still nowadays very challenging for everyday’ s practice. The initial evaluation of the patient with suspected epilepsy is multifaceted and includes a careful history, diagnostic evaluation (EEG and brain imaging) and prompt referral to an epilepsy specialist to clarify seizure types and epilepsy syndrome. Screening for mental health conditions also should be considered, along with neurocognitive testing when deficits of language, memory, learning, attention, or executive function are present.
What is the aim of the project?
This study aims to investigate the best initial approach at the neurological ambulatory care in new-onset seizures and getting the right diagnosis following inpatient neurological evaluation of seizure disorders, in order to provide the optimal treatment for the patient.
What techniques and methods are used?
1. Taking medical history and doing physical examination (measuring temperature!) 2. Standard lab tests – blood analysis, glucose level, electrolytes… 3. Electroencephalography and electrocardiography 4. MRI 5. CT scan if trauma and/or bleeding is suspected 6. Lumbar puncture, if brain infection is suspected
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Student is expected to perform clinical examination of the patient, to evaluate his/her condition and participate in making a decision about further course of treatment. Student will also be expected to perform a literature review, and to form the database for patients with same or similar signs and symptoms. Student can take out the blood for the lab analysis, do ECG and EEG, and perform lumbar puncture. He/she will also be expected to analyze MRI and CT scan.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Yes, upon request
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report - No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Students should have attended Neurology, Pediatrics and Internal Medicine classes, basic experience in physical examination
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
- Prakash Paliwala; Benjamin R. Wakerleyb; Leonard L.L. Yeoa et al. Early electroencephalography in patients with Emergency Room diagnoses of suspected new-onset seizures: Diagnostic yield and impact on clinical decision-making. Elsevier. 2015; 31:22-26.
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