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Differential diagnosis and therapy of demyelinating diseases of the nervous system
Russian Federation (HCCM Russia) - Ural State Medical Academy, Ekaterinburg
Department of Neurology, neurosurgery and Medical Genetics of Ural State Medical University
Prof. Larisa I. Volkova
Dr.Ekaterina IU. Moskvina, Dr. Olga V. Tsyganenko
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
In recent years, the world has been a steady trend towards increase the frequency of demyelinating diseases, a growing number of cases with the clinical beginning in children and adults above the age of 45 years, the nature of the development of demyelinating diseases has changed, they are recorded in the non-standard geographic areas. The situation is exacerbated by insufficient knowledge of this extremely heterogeneous in clinical manifestations and prognosis group of diseases. This determines the relevance of their study, and from the clinical point of view - the importance and difficulties of the differential diagnosis, which determines the further management tactics of patients.
What is the aim of the project?
The aim of the project is to study algorithms for diagnosis and management of patients with demyelinating diseases.
What techniques and methods are used?
Clinical methods: Physical examination of patients in neurology unit Instrumental methods: MRI - magnetic resonance imaging
What is the role of the student?
- The student will mainly observe
- If the project is clinical
- the student will take active part in the clinical examination
- If the project is clinical
- the student will be allowed to work with patients
- The tasks of the student will be performed on his/her own
What are the tasks expected to be accomplished by the student?
Participation in patients examination: - General Appearance, including posture, motor activity, vital signs and perhaps meningeal signs if indicated - Mini Mental Status Exam, including speech observation - Cranial Nerves, I through XII - Motor System, including muscle atrophy, tone and power - Sensory System, including vibration, position, pin prick, temperature, light touch and higher sensory functions - Reflexes, including deep tendon reflexes, clonus, Hoffman's response and plantar reflex - Coordination, gait and Rhomberg's Test Estimating results of laboratory tests, MRI- magnetic resonance imaging, questionnaire of patients, statistical analysis of data, using STATISTICA 6.0
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Yes: 1 seminar with discussion, 2 lectures
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster - The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic knowledge in Neurology Basic knowledge in statistical analysis Basics of neurological examination
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
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