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Understanding the Molecular Mechanisms of How Obesity Effects Mammary Tumor Growth Using Transgenic Mice Models
Turkey (TurkMSIC) - Yeditepe University, Istanbul
Department of Medical Biology, Yeditepe University School of Medicine
Dr. Soner Dogan
Dr. Soner Dogan
Type of Research Project
- Basic science
What is the background of the project?
Obesity is a complex disorder involving an excessive amount of body fat. Obesity isn't just a cosmetic concern. It increases your risk of diseases and health problems, such as heart disease, diabetes and high blood pressure. A mammary tumor is a tumor originating in the mammary gland.There are many differences between mammary tumors in animals and breast cancer in humans, including tumor type, malignancy, and treatment options. To understand the molecular mechanisms of how obesity triggers mammary tumor development or how calorie restriction prevents it. DNA isolation, ELISA, WESTERN BLOTT, PCR, some other assays to measure some blood parameters. We will intensely work with transgenic mice (feeding, body weight measurement, blood collection, tumor measurement etc
What is the aim of the project?
What techniques and methods are used?
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster - The student will prepare a presentation - The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Student should have already passed exams in biochemistry, physiology and cell biology. Student should be familiar with lab equipment, must be reliable and willing to learn new information and lab techniques. Student should be easy going.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system
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