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Biophysical characterization of bone tissue using spectroscopic and/or scanning electron microscopy (SEM) techiques
Greece (HelMSIC) - University of Ioannina, Ioannina
Biophysics and Medical Physics
Department of Medical Physics, Faculty of Medicine, School of Health Sciences, University of Ioannina, Greece
Prof. M. Tzaphlidou
Nikolaos Kourkoumelis, Assistant Professor
Type of Research Project
- Basic science
What is the background of the project?
Structural and compositional heterogeneity of bone contributes to osseous properties such as stiffness, hardness, elasticity and overall strength. Probing the atomic as well as the molecular composition is a fascinating research area to study normal and diseased bone tissues. We are particularly interested in assessing structural and molecular variations of the osteoporotic bone. The aim of the project is to study cortical and trabecular bone tissues using spectroscopic and/or electron microscopy methods. Techniques : FTIR spectroscopy; Raman Spectroscopy; Scanning electron microscopy
What is the aim of the project?
What techniques and methods are used?
What is the role of the student?
- If the project includes “lab work”
- the student will take active part in the practical aspect of the project
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Follow the supervisor throughout the Project and participate in some experiments
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Yes, if needed
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
The student is expected to: (i) have basic knowledge of lab work (chemicals and labware handling), (ii) be able to apply methods and protocols found in the literature and (iii) have working knowledge of common software packages (e.g. Microsoft Office, etc.). Advanced computing skills are definitely a plus.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
- Hadjipanteli A. Kourkoumelis N. Fromme P. Huang J. Speller R.D. 2016. Evaluation of the 3D spatial distribution of the Calcium/Phosphorus ratio in bone using computed-tomography dual-energy analysis. Physica Medica 32. 162-168
- Hadjipanteli A. Kourkoumelis N. Speller R. 2014. Evaluation of CT DEA performance on Ca/P ratio assessment in bone apatite using EDX. X Ray Spectrometry 43. 286-291
- Kourkoumelis N. Lani A. Tzaphlidou M. 2012. Infrared spectroscopic assessment of the inflammation-mediated osteoporosis (IMO) model applied to rabbit bone. Journal of biological physics 38. 623-635
- Kourkoumelis N. Balatsoukas I. Tzaphlidou M. 2012. Ca/P concentration ratio at different sites of normal and osteoporotic rabbit bones evaluated by Auger and energy dispersive X ray spectroscopy. Journal of biological physics 38. 279-291
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