Projects
Name
Investigations on Pathogenicity factors of coagulase negative Staphylococci
University
Germany (bvmd) - Ruhr-Universitaet, Bochum
Domain
Microbiology
Departement
Abteilung fuer Medizinische Mikrobiologie, Universitaetsstr. 150, 44801 Bochum, Germany
Head
Prof. Dr. Soeren G. Gatermann
Tutor
Dr. rer. nat. Nils Pfenningwerth
Languages
English, German
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No yes yes yes yes No No yes yes yes yes
Type of Research Project
- Basic science
What is the background of the project?
Carbapenem resistance in Gram-negative bacteria of clinical importance is a threat to healthcare systems worldwide. Carbapenem resistance is mainly based upon production of carbapenemases and decreased membrane permeability.
What is the aim of the project?
Our research objectives are the identification and characterization of these mechanisms.
What techniques and methods are used?
antimicrobial susceptibility testing, phenotypic detection of resistance mechanisms, genotypic characterization of resistance mechanisms, construction of carbapenem resistant mutants
What is the role of the student?
What are the tasks expected to be accomplished by the student?
phenotypic detection and characterization of carbapenem resistance mechanisms
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
1
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Knowledge in the field of microbiology and some kind of lab skills would be preferable, but are not absolutely necessary. A seminar talk (Powerpoint-presentation) and a report that summarizes the outcome of the work is demanded.
Are there any legal limitations in the student’s involvement
No
Hours
8
Type of students accepted
This project accepts:
- Medical students
Articles
- FRANK
- K. L.
- DEL POZO
- J. L. & PATEL
- R. 2008. From clinical microbiology to infection pathogenesis: how daring to be different works for Staphylococcus lugdunensis. Clin Microbiol Rev
- 21
- 111-33.
- Kuroda M
- Yamashita A
- Queenan AM; Bush K. Carbapenemases: the versatile betalactamases.Clin Microbiol Rev. 2007 Jul;20(3):440-58