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Prognostic and predictive value of selected molecular changes in the head and neck cancers.
Poland (IFMSA-Poland) - Medical University of Lublin, Lublin
Department of Human Physiology, Radziwillowska 11, 20-080 Lublin, Poland
Teresa Malecka-Massalska, M.D., Ph.D., Assoc. Prof.
Radoslaw Mlak, PhD
Type of Research Project
- Basic science
What is the background of the project?
Clinical research project with lab work. The information stored in deoxyribonucleic acid (DNA; single nucleotide polymorphisms, mutations), ribonucleic acid (RNA; gene expression) or miRNA (regulation of level of gene expression) are responsible for the proper functioning of the proteins involved in pathomechanism of cancer development, metabolism of drugs and responsible for cell radiosensitivity. Thus this biomarkers may be useful in: early detection of cancer as well as, monitoring and prediction of outcome of patients with cancer undergoing radiotherapy, chemotherapy or surgical treatment.
What is the aim of the project?
Evaluation of prognostic and predictive value of selected molecular changes in the head and neck cancers.
What techniques and methods are used?
The acquisition of appropriate knowledge and its practical application allowing to active participation in: design of experiments, laboratory research: isolation of nucleic acids (DNA, RNA, miRNA), conducting PCR, reverse transcription and real-time PCR, electrophoresis.
What is the role of the student?
What are the tasks expected to be accomplished by the student?
Participation and self-development.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
No particular skills.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system
- Puram SV; Rocco JW. Molecular Aspects of Head and Neck Cancer Therapy. Hematol Oncol Clin North Am. 2015 Dec;29(6):971-92. doi: 10.1016/j.hoc.2015.07.003. Epub 2015 Oct 17
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