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Use of pig islets to treat human diabetes type 1
Belgium (BeMSA) - Université Catholique de Louvain, Brussels
Experimental and Transplantation surgery laboratory
Type of Research Project
- Basic science
What is the background of the project?
Diabetes of type 1 and 2 are the most important diseases of the next decade, especially type 2. The treatment, however, is still not ideal and the adherence is low. A lot of patients with diabetes suffer from secondary complications in the low run. We hope to find a treatment that is more sustainable. More info: search for P. Gianello on PubMed NCBI
What is the aim of the project?
Try to find ways to replace the chronic and daily injection of exogenous insulin by transplanting cells producing insulin in patients suffering from diabetes
What techniques and methods are used?
isolation of pig islets, encapsulation/ implantation of pig islets in vivo in animal models or in vitro to study the insulin production
What is the role of the student?
- The tasks of the student will be performed on his/her own
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Knowledge of different ways to do research in that field, cell culture; insulin assessment, transplantation of cells. Participating in all the laboratory activites, including lab work, daily assays, working with animal models. The student will be able to actively participate in the surgery and the analysis of the data. He will be taught the different skills under supervision of the tutor. In the end the student should be able to perform the basic tasks alone. The student will learn more about diabetes disease and research which can be developed in the field of insulin producing cells
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
During the internship there is personalized teaching.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
All steps are doable by any student who is focused on and involved in his work; A 2-3 pages scientific report will be asked at the end of the period.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system - Students in biomedical fields
- More info: search for P. Gianello on PubMed NCBI
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