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Atypical small acinar proliferation of the prostate: Morphological characteristics, morphogenesis and nosological positions
Russian Federation (HCCM Russia) - South Ural State Medical University, Chelyabinsk
Prof. Evgeniy L.Kazachkov
Prof. Angela A.Kazimirova, Dr. Irina R. Usupova
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
Prostate cancer among men is one of the leading positions in the structure of oncological diseases. Early detection of this disease is necessary to optimize complex morphological diagnosis preneoplastic processes and prostate cancer.
What is the aim of the project?
to give morphological characteristics to atypical small acinar proliferation of the prostate to study mechanisms and pathomorfological features of atypical small acinar proliferation of the prostate to determine features of morphogenesis and options atypical small acinar proliferation of the prostate with nosological positions.
What techniques and methods are used?
For this research project we will use Morphological methods: initial rewiev of the hematoxylin and eosin stained slides. Immunohistochemical methods: tissue-block immunohistichemical antibody test (antibody coctail for Ki-67 and Bcl-2). Statistical methods:nonparametric method of Manna Whitney and Mediana using Statistica 6.0
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- If the project includes “lab work”
- the student will take active part in the practical aspect of the project
- If the project is clinical
- the student will take active part in the clinical examination
What are the tasks expected to be accomplished by the student?
The student will be able to independently perform a physical examination of patients, assist with autopsy (cutting of pathological materials under the supervision of the tutor), work in the histochemical laboratory: histological and morphometric studies of autopsy biomaterials and statistical analys of the results using program Statistica 6.0
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation - The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basical knowledge of human anatomy( exam or test should le passed) Final test or exam in Pathology should be passed
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
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