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Features of the lesion of ears, nose and throat organs from HIV-infected patients at different stages of the disease
Russian Federation (HCCM Russia) - Perm State Medical Academy, Perm
Department of Infectious Diseases, Department of Otorhinolaryngology, Perm Regional Clinic
Dr. Alexey M.Elovikov
Drs. A.O. Charushin, I.P.Charushina, A.M. Elovikov
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
HIV infection is one of the most actual problem in the modern world. Progressive Immunodeficiency in HIV-infected patients leads to the development of opportunistic infections of different organs and systems, including ENT(ears, nose and throat) organs.
What is the aim of the project?
The aim of the project is to study the features of the lesion of ENT organs from HIV-infected patients at different stages of the disease.
What techniques and methods are used?
Techniques and methods that will be used: Otorhinolaryngological examination virological and bacteriological methods: Virus Isolation, The complement fixation test (CFT), Haemagglutination Inhibition Test, , Immunofluorescence (IF), Microscopy statistical methods: STATISTICA 6.0 comprehensive statistics package
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
What are the tasks expected to be accomplished by the student?
- Work in infectious hospitals: the joint (with doctor) examination of HIV-positive patients - The capture of smears in HIV-positive patients from the nasal cavity, the tonsils, external ear canal. - Work in the laboratory: examination of smears on the fungi of the genus Candida (C. albicans etc). - The discussion of the results. The hypotheses. Working with documents.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Preliminary readings, courses on the topic of HIV infection in otorhinolaryngology, modern trends in the spread of HIV infection
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation - The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
To pass the exams: Otolaryngology, Infectious Diseases, Microbiology
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
- - Oropharyngeal candidiasis in the era of antiretroviral therapy(George R. Thompson; III;MD;a;bPayal K. Patel; MD;a William R. Kirkpatrick; Texas UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AND SOUTH TEXAS ETERANS HEALTH CARE SYSTEM)
- - Gammainterferon treatment for resistant oropharyngeal candidiasis in an HIV-positive patient. (Bodasing N; Seaton RA; Shankland GS; Pithie A.J AntimicrobChemother 2002)
- - Detection and significance of fluconazole resistance in oropharyngeal candidiasis in human immunodeficiency virus-infected patients.(Revankar SG; Kirkpatrick WR; McAtee RK; Dib OP; Fothergill AW; Redding SW; et al. J Infect Dis 1996)
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