Projects
Name
Analysis of the effects of laparoscopic sleeve gastrectomy, with and without antral preservation, on gastric physiology and metabolic response: a randomized study
University
Catalonia (AECS) - University Rovira i Virgili (URV), Tarragona
Domain
General Surgery
Departement
Surgery service. University Hospital of Sant Joan
Head
Daniel del Castillo D
Tutor
Merce Hernandez, Fatima Sabench, Santiago Blanco, Antonio Sanchez, Jesus Sanchez, Joan Domenech
Languages
English, Spanish accepted but not necessary
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No No No No No Yes No No No No No
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Sleeve gastrectomy is a restrictive procedure. It greatly reduces the size of the stomach and limits the amount of food that can be eaten at one time. The main aim of the project is to standardize the optimum distance between the pylorus and the laparoscopic incision (the two options are 3 or 8 cm from the pylorus)depending on the effects on gastric emptying, the strain and hormonal changes (ghrelin,GLP-1 and PYY). Another aim is to determine whether the topographic distribution of the ghrelin-producing cells in the surgical specimen can contribute to a better approach to the metabolic-surgical nexus (by discovering the role of the gastric antrum)
What techniques and methods will be used? The clinical trial was randomized and open to surgical groups. Response was defined as variation before-after intervention and they were compared with a healthy control group. Study subjects: morbidly obese patients with a BMI greater than or equal to 45 kg/m2 The student will have access to our database with the outcome information of the patients.
What is the aim of the project?
The main aim of the project is to standardize the optimum distance between the pylorus and the laparoscopic incision (the two options are 3 or 8 cm from the pylorus) depending on the effects on gastric emptying, the strain and hormonal changes (ghrelin, GLP-1 and PYY). Another aim is to determine whether the topographic distribution of the ghrelin-producing cells in the surgical specimen can contribute to a better approach to the metabolic-surgical nexus (by discovering the role of the gastric antrum).
What techniques and methods are used?
The clinical trial was randomized and open to surgical groups. Response was defined as variation before-after intervention and they were compared with a healthy control group.
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Assist to surgical sessions and a review of clinical histories. The student is expected to acquire the abilities related to the experimental line that he/she will be working on and, by the end of the stay is expected to be able to perform his/her task by him/herself.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
No
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster
- The student will prepare an abstract
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
It is necessary to be have had General Surgery practices and Digestive Lectures.
Are there any legal limitations in the student’s involvement
No
Hours
6
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
- Students in biomedical fields
Articles
- http://www.ncbi.nlm.nih.gov/pubmed/22683132
- http://www.ncbi.nlm.nih.gov/pubmed/22434197
- http://www.ncbi.nlm.nih.gov/pubmed/22054159