Projects
Name
Molecular and Immunological Study of Fungal Pathogen
University
Thailand (IFMSA-Thailand) - Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok
Domain
Pathology
Departement
Department of Pathology, Ramathibodi Hospital, Mahidol University
Head
Assoc. Prof. Dr. Sansanee Wongwaisayawan
Tutor
Assistant Professor Theerapong Krajaejun
Languages
English or Thai
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
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Type of Research Project
- Basic science
What is the background of the project?
The project is focusing on the exploration of biology and pathogenesis of fungal infection, using Pythium insidiosum as a study model. P. insidiosum causes an endemic and life threatening infectious disease.
What is the aim of the project?
To understand biology and pathogenesis of P. insidiosum and develop a better diagnosis and potential treatment option.
What techniques and methods are used?
DNA/RNA Extraction, PCR, Gene Cloning and Expression, Bioinformatic Analysis using several computional tool.
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
What are the tasks expected to be accomplished by the student?
Preform molecular research relevant to the patients with fungal infection.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
1
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster
- The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Universal precaution technique, aseptic/sterile technique. No legal limitations.
Are there any legal limitations in the student’s involvement
No
Hours
7
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
- Pre-Medical students from the American-British system
Articles
- Clinical and epidemiological analyses of human pythiosis in Thailand. Clin Infect Dis. 2006 Sep 1;43(5):569-76.
- Transcriptome analysis reveals pathogenicity and evolutionary history of the pathogenic oomycete Pythium insidiosum. Fungal Biol. 2014 Jul;118(7):640-53.
- Efficiency comparison of three methods for extracting genomic DNA of the pathogenic oomycete Pythium insidiosum. J Med Assoc Thai. 2014 Mar;97(3):342-8.