Projects
Name
Antitumoral effect of nutraceuticals on mesenchimal cell tumors lines
University
Universita degli Studi di Roma 'Tor Vergata'
Domain
Oncology
Departement
Department of clinical sciences and translational medicine
Head
Prof. Andrea Modesti
Tutor
Prof. Roberto Bei
Languages
English
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No No No No No Yes No No Yes No No
Type of Research Project
- Basic science
What is the background of the project?
The rate of mesenchimal cell tumors is increasing worldwide and despite advances in treatment, the survival rate of patients has not considerably changed over the last two decades. Dietary polyphenols can be employed to inhibit the growth of cancer cells.
What is the aim of the project?
The aim of the study is to determine whether different polyphenols can affect the proliferation and signaling transduction pathways of mesenchimal tumors cells.
What techniques and methods are used?

-Sulforhodamine B assay
-Western blotting
-Facs analysis
-Immunofluorescence
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
What are the tasks expected to be accomplished by the student?
The student will learn the techniques used and after he/she will be able to carry out these techniques, he/she will be involved not only in the theoretical part of the project, but also in the experimental part.
The student will learn the techniques used and effects of polyphenols on cancer cells.

The outcome is dependent on the results of the project.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Preliminary readings
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Knowledge of cell biology.

For the use of students considering participating in the project, further information can be found from the following articles:
Benvenuto et al Front. Biosci. (Landmark edition) 2013, 18: 1290-1310
Izzi et al Front. Biosci. (Landmark edition) 2012, 17 : 2396- 2418
Mauselli et al Front Biosci. 2012, 17, 498-508
Are there any legal limitations in the student’s involvement
No
Hours
6
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
Articles
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