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Learning how to measure the pancreatic beta-cell mass and how to isolate the pancreatic islets in rats
Federal University of Santa Catarina (UFSC)
Department of Physiological Sciences, Center of Biological Sciences, Federal University
Prof. Moacir Serralvo Faria
Prof. Alex Rafacho
Portuguese, English, Spanish
Type of Research Project
- Basic science
What is the background of the project?
The beta-cell mass comprises the total amount of insulin-producing cells in the endocrine pancreas that account for the insulin secretion under several physiological conditions. The importance of beta-cell mass can be observed during obesity and type 2 diabetes mellitus (T2DM). Additionally, isolation of the pancreatic islets is an interesting approach to study the insulin secretory process, which is another crucial process to maintain the glucose homeostasis in face of the peripheral insulin resistance likely in obesity and T2DM.
What is the aim of the project?
What techniques and methods are used?
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
The student must have no problem with animal (rat) handling and it would be welcome if his/her had interest in the area of the Endocrine Pancreas & Metabolism.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
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