[Morelia] Brain damage and its impact on the muscle,
Universidad Michoacana de San Nicolas de Hidalgo
Research Unit
Dr. Punzo Bravo Guillermo
Dr. Punzo Bravo Guillermo
English, Spanish
4 weeks
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No Yes Yes No Yes No No No Yes Yes Yes No
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
Severe traumatic, hypoxic, or vascular injury of the central nervous system often leads to various signs of brain damage, which are collectively termed upper motor neurone syndrome or pyramidal syndrome. Traditionally, components of pyramidal syndrome are divided into positive and negative features. Positive signs are phenomena characterized by a variety of muscle overactivity types. These types can be divided into spasticity (as primarily defined as exaggerated tonic and phasic stretch reflexes of skeletal muscle after passive stretch) on the one hand, and non-spastic muscle overactivity on the other, such as co-contraction of antagonist muscles, associated reactions (synkinesias), flexor and extensor spasm, and dystonia. Negative signs are those that have been lost such as paresis, dexterity, and selective control of limb movement.
What is the aim of the project?
The aim of the project is to established for three to five years, where muscular effects are analyzed by the brain damage, assessing the constraints and trying to give a therapeutic solution to improve the situation, taking as a sample hospital patients.
What techniques and methods are used?
The project will take place in the area of internal medicine and hospital emergency; where the student support so guided by the tutor both collecting data and samples to be analyzed and subsequently collected in the database of the research project, where the tutor explain the functions that the student will have to do in this part of the protocol. Inclusion criteria for the study are patients after severe brain injury caused by trauma, intracerebral haemorrhage, or severe cerebral hypoxia. The time post-injury for all patients will be between 90 and 365 days. Exclusion criteria are patients who are undergoing treatment. Treatment will be randomly
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Written report for the end of the exchange
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Students must have basic knowledge in the field of research and in its academic program have taken the subjects of medical semiology, pharmacology and neurology (or equivalent if applicable). The only limitation is to respect patient autonomy.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts:
- Medical students
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