Impacts of Hypervariable Control Regions of Polyoma virus BK on Viruria in Kidney Transplant Recipients
Taiwan (FMS-Taiwan) - Chang Gung University, Taipei
Infectious Diseases
Department of Biomedical Sciences, Chang Gung University
Prof. Li-Man Hung
Dr. Robert YL Wang
4 weeks
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
No No No No No No Yes Yes Yes No No No
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
BK virus (BKV) is a polyomavirus that cause of allograft dysfunction among kidney transplant recipients. The role of BKV infection in non-renal solid organ transplant recipients is not well understood neither for the relation between various BKV strains with occurrence of BKV viruria.
What is the aim of the project?
This project aims to determine the prevalence of BKV infection and identified of BKV various strains from the post-kidney transplant recipients.
What techniques and methods are used?
The techniques used include genomic DNA isolation, real time quantitative PCR, gene construction, cell culture, and DNA/RNA transfection.
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The student needs to carry out some experiments under the instruction by the tutor or research assistant in the laboratory. The students have to compare the multiple variant NCCRs in positive BKV viruria with negative BKV viruria patients with the association with high- or low-urinary BKV load in patients.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic concepts of biochemistry and molecular biology.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
- Pre-Medical students from the American-British system
- 2016;Scientific Reports (6):28491:{ The association between polyomavirus BK strains and BKV viruria in liver transplant recipients}