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FinnBrain Birth Cohort Study ? Neurodevelopment and Vulnerability to Stress
Finland (FiMSIC) - University of Turku, Turku
University of Turku, Faculty of Medicine, Institute of Clinical Medicine
Prof. Hasse Karlsson
Prof. Hasse Karlsson, project coordinator Eija Jossandt
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
Little is known about the mechanisms of gene-environment influence on human brain development during pre- and postnatal periods and early childhood and how the trajectories of brain development are linked with e.g cognitive, emotional, and behavioral outcomes. In FinnBrain early programming of the stress, emotion, immune and sleep regulating systems and how maternal depression, anxiety and stress influences these are assessed. Brain developmental trajectories are investigated leading to selected child developmental milestones and their relation to later emergence of psychiatric or somatic illness, especially depression, cognitive decline and cardiovascular disease. To study these matters a large birth cohort (started 2011) has been recruited and the final N is 4 000 women, their partners, and children. The follow-up of both children and their parents will continue for several decades.
What is the aim of the project?
The aim of the project is to study the gene-environment interplay in the structural and functional development of the central nervous system (CNS) and their relation to childhood development and later morbidity and to trace mechanisms behind e.g. individual vulnerability to stress, depression, congnitive decline and cardiovascular disease, which are all major public health issues in high-income countries.
What techniques and methods are used?
What is the role of the student?
What are the tasks expected to be accomplished by the student?
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
The tasks will be customized according to the students previous experience so no formal skills are required. There may be some limitations in participating in clinical investigations of the families
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
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