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Vitamin D and metabolic syndrome in children and adolescents
Greece (HelMSIC) - University of Ioannina, Ioannina
Child Health Department, Medical School, University of Ioannina
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
In recent years it has become clear that vitamin D has many extraosseous functions. One of them is related to metabolic functions related to insulin sensitivity and ;-cell function. Hence vitamin D deficiency has been implicated as a risk factor in obesity and the type 2 diabetes. A lot of research has been carried out mainly in adults while in children our knowledge is very scarce. The aim is to investigate any possible associations of vitamin D with obesity/metabolic syndrome in children and adolescents, and to relate vitamin D to lipid metabolism and adipocytokines Mainly ELISA assays (enzyme linked immunosorbent assays) and chromatography
What is the aim of the project?
What techniques and methods are used?
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- If the project includes “lab work”
- the student will take active part in the practical aspect of the project
What are the tasks expected to be accomplished by the student?
Assist in the Lab Work of the project
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Bring your own lab coat.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system
- Threshold for effects of vitamin D deficiency on glucose metabolism in obese female African-American adolescents. Ashraf A et al. J Clin Endocrinol Metab 2009; 94(9): 3200-6
- Hypovitaminosis D in obese children and adolescents: relationship with adiposity
- insulin sensitivity
- ethnicity and season. Alemzadeh R et al. Metabolism 2008: 57(2): 183-91
- Vitamin D in relation to metabolic risk factors
- insulin sensitivity and adiponectin in a young Middle-Eastern population. Gannagé-Yared M-H et al. Eur J Endocrinol 2009; 160: 965-71
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