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Body composition changes in ageing HIV infected patients: the complex interplay between low muscle mass, lipodystrophy and osteopenia.
Università degli Studi di Modena e Reggio Emilia
Clinica delle malattie infettive, Largo del Pozzo 71 - Modena
Prof.ssa Cristina Mussini Mail: firstname.lastname@example.org
Type of Research Project
- Clinical Project without Laboratory work
What is the background of the project?
Body composition is a key determinant of ageing phenotype. HIV patients (pts) on ART are frequently affected by lipodystrophy (LD) and ostreopenia/osteoporosis (O/O) and in the aging process they experience a decline in fat free mass index (FFMi=FFM/h2) similar to uninfected individuals.
What is the aim of the project?
In an ageing HIV-infected cohort we aimed to describe the interaction between anthropometric changes of FFMi, Leg fat % (surrogate for lipoatrophy), VAT/TAT (surrogate for lipohypertrophy) and lumbar BMD (surrogate for O/O). aim: Describe the interaction between anthropometric changes of FFMi, Leg fat % (surrogate for lipoatrophy), VAT/TAT (surrogate for lipohypertrophy) and lumbar BMD (surrogate for O/O).
What techniques and methods are used?
Observational prospective study including HIV+ men older than 50 years or HIV+ post-menopausal women. Measured changed in: FFMi, leg fat %, BMD (using DXA) and in VAT/TAT (using abdominal CT) were performed at least 1 year apart.
What is the role of the student?
What are the tasks expected to be accomplished by the student?
The student is expected to help with the data collection as well as collaborating in interviewing and examining the patients, as needed. There are no additional presentations or contributions needed but the student is expected to help with the drafting of the paper that will be published at the end of the research project. The students will deepen his/her knowledge about HIV and acquire all the skills related to the treatment of patients with this disease.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Occasional seminars and lectures. The students can search on PubMed all the articles written by “Giovanni Guaraldi” or simply write the name of the research project.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster - The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
The student should have a good knowledge of English and must have passed the exam of infectious diseases. There are no limitations.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system
- The students can search on PubMed all the articles written by “Giovanni Guaraldi” or simply write the name of the research project.
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