Projects
Name
[Sfax]The study of allergen-specific Immunoglobulin E
University
Tunisia (ASSOCIA-MED) - University of Sfax/ Faculty of Medecine of Sfax, Sfax
Domain
Immunology
Departement
The immunology laboratory Habib Bourguiba university hospital of Sfax, Tunisia
Head
Pr. Hatem Masmoudi
Tutor
Dr. Sawsan Feki
Languages
English - French
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
Yes No No No No Yes Yes No Yes Yes No No
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
The exposure to allergens has immeasurably evolved in the last decade (the change of the indoor life style, the anthropogenic environmental modifications which has an impact on the vegetal development, pollution...) affecting the level of the individual allergic sensitivity and causing the considerable increase of allergies in the whole world including Tunisia. Thus, the knowledge and the follow up of the different types of these responsible allergens in each region are essential.
What is the aim of the project?
This project aims to study and determine the main allergens shown by the specific IgE test in our laboratory (type, distribution according to age, gender, the areas of origin, the requesting department...) and to demonstrate the contribution of anti-CCD IgE (cross-reactive carbohydrate determinants) in the allergy test.
What techniques and methods are used?
 Total IgE dosing with chemiluminescence  Searching for specific IgE using a multi-allergen test with a specific response : semi-quantitative immun dot technique.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
 Practice the different immunological techniques used after a period of learning:  Total IgE dosing with chemiluminescence  Searching for specific IgE using a multi-allergen test with a specific response: semi- quantitative immun dot technique.  Gather clinical informations,  Analyze and interpret the results.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Preliminary readings in French or English will be provided to the exchange student at the beginning of his exchange period.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster
- The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
- A white coat is obligatory for this clinical project.
- There are approximately 6 hours of work per day.
- The exchange students participating in this project should be a medical student who has already studied Immunology, Pediatrics and Pulmonology (Respiratory diseases).
Are there any legal limitations in the student’s involvement
No
Hours
6
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
- Pre-Medical students from the American-British system
Articles
- - la revue française d'allergologie: (exemple: article "l'augmentation de la sensibilisation allergique: rôle de l'allergène" A.Casset (2009))
- - Archives de pédiatrie ("allergènes responsables d'allergie respiratoire: les pneumallergènes" A. Deschildre (1999))
- - Nutrition clinique et métabolisme ("allergies alimentaires: mécanismes physiopathologiques; identification des allergènes alimentaires" Jean-Michel Wal (2003))