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Origins of Colonic Cancer in young males. (Alexandria University)
Egypt (IFMSA-Egypt) - Alexandria University, Alexandria
Department of Colorectal Surgery - Alexandria Faculty of Medicine
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
Colon Cancer is considered as the second most common cancer among Hispanic men, Scientists believe they've discovered how a mutation in the APC gene causes colon cancer. A study published in the journal Cancer Research found that the APC gene normally limits the expression of a protein (survivin) that prevents stem cells from dying. When the APC gene is altered, stem cells in the colon end up overpopulating because the APC gene is no longer doing its job and the survivin is basically having a field day. This overpopulation of cells in the colon, scientists say, leads to colon cancer. The aim is to go deeper in studying the origins of colon cancer in men and reach a solid ground regarding the origins of colon cancer in men. Attendance and Observation at clinical rounds, Participation in the clinical assessment with the tutor, Data collection and analysis.
What is the aim of the project?
to go deeper in studying the origins of colon cancer in men and reach a solid ground regarding the origins of colon cancer in men. Attendance and Observation at clinical rounds, Participation in the clinical assessment with the tutor, Data collection and analysis. -state the diseases and conditions associated with colonic cancer. -determination of risk factors in young males. -create clear image about pathophysiology of the disease in young males.
What techniques and methods are used?
case reports, systematic reviews and case series
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
• Attendance and observation at clinical rounds • Take history from patients • Participation in clinical assessment with the tutor • Data collection • Data analysis • Data report
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
The student must have the basic knowledge about the project. White lab coat and stethoscope are mandatory for attendance of the cinical rounds.
Extra references: The American Journal of Surgery, Volume 187, Issue 3, Pages 343-348 Jessica B O'Connell, Melinda A Maggard, Edward H Livingston, Cifford K Yo
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
- Siegel R; Ma J; Zou Z; Jemal A. Cancer statistics; 2014. CA Cancer J Clin. 2014;64(1):9–29 Erratum in: CA Cancer J Clin. 2014;64(5):364
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