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[Monterrey] Characterization of the morphological damage and funtional deterioration of a model of global cerebral isquemia in old rats.
Universidad Autonoma de Nuevo Leon
Department of Human Anatomy
Santos Guzman Lopez
Alejandro Quiroga Garza
English and spanish
Type of Research Project
- Basic science
What is the background of the project?
Experimental studies of cerebral isquemia in senescent rats have not been done. Most studies of isquemia are done in young animals, even though cerebral isquemia is most commonly presented in senescent patients. It is important that the developed models for cerebral isquemia have chronic evaluations and morphological and functional testing as well.
What is the aim of the project?
Characterization of the morphological damage and functional deterioration of the model of global cerebral ischemia.
What techniques and methods are used?
The main technique will be the four- vessel occlusion surgery as a model of global cerebral isquemia. Additional histological techniques such as tunnel will be needed. Morrison
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Written report for the end of the exchange
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Preliminary readings and seminars.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic anatomy knowledge
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system
- Duverger; D.; & MacKenzie; E. T. (1988). The quantification of cerebral infarction following focal ischemia in the rat: influence of strain; arterial pressure; blood glucose concentration; and age. Journal of Cerebral Blood Flow & Metabolism; 8(4); 449-461.
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