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Roles of microcirculatory system in tissue regeneration and tumor progression
Tokyo Women's Medical University
Department of Anatomy and Developmental Biology Tokyo Women
Prof. Taichi Ezaki, M.D., Ph.D.
Dr. Masae Morishima, DVM, Ph.D. (and other PhD staffs depending on the project)
Type of Research Project
- Basic science
What is the background of the project?
Project includes analyses of neovascularization mechanism in regenerative medicine. This project can also include characterization of tumor blood vessels and lymphatic vessels.
What is the aim of the project?
To feedback the data to the clinical understanding in regenerative medicine. As to tumor angiogenesis, the future goal would be to contribute to the growth control of neoplasms.
What techniques and methods are used?
General morphological techniques in histology, cell biology, or molecular biology, such as immuno-histochemistry, in situ hybridization, computer-based image analysis for 3-D structures and electron microscopy. In vivo animal surgical operation and in vitro cell culture techniques are undertaken.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
The student herself should learn and get skills for handling animals, making tissue sections, immunostaining and observation using various microscopes. The student may also learn many other useful techniques required for the study according to the situation.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Every Friday we hold a seminar and round-table discussions with all staffs. The student is supposed to attend these meetings.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster - The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Nothing special. But check if the student would have any problems for animal handling, especially allergy to rodents (mice and rats). Check our home page (URL: http://www.twmu.ac.jp/Basic/ana-2/index.html), and read some of our papers that the student feels interest.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
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